Scientific Publications by FDA Staff

Rapid Commun Mass Spectrom 1993 Nov;7(11):971-88

Multiresidue pesticide analysis by ion-trap mass spectrometry.

Cairns T, Chiu KS, Navarro D, Siegmund E

The ion trap has been demonstrated to be able to detect and quantify 245 target pesticides extracted via the Luke method while providing concurrent confirmation of presence via full scan data at the sub-ppm level. The precision and accuracy of the analytical approach was determined to be no greater than 15% relative standard deviation. A comparison study of over 100 incurred residues analyzed by the ion trap and gas chromatography with an array of element-selective detectors has indicated that sample clean-up will probably be necessary before quantification is acceptable for all target compounds. The data obtained using a combination of gas chromatography and mass spectrometry and presented for 250 target pesticides constitutes the basic information required to duplicate and extend the methodology.