FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

Current/Resolved Shortages
Discontinuations
Therapeutic Categories
New and Updated

A drug receives Resolved status when the Drug Shortages Staff (DSS) determines that the market is covered, based on information from all manufacturers. The market is considered covered when supply is available from at least one manufacturer to cover total market demand. However, some manufacturers may not have all presentations available. DSS monitors the supply of products with Resolved status. For the most current supply information, contact the manufacturers.

Generic Name or Active Ingredient	Status
Acetazolamide Injection	Currently in Shortage
Amifostine Injection	Currently in Shortage
Amino Acids	Currently in Shortage
Amoxapine Tablets	Currently in Shortage
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets	Currently in Shortage
Anagrelide Hydrochloride Capsules	Currently in Shortage
Asparaginase Erwinia Chrysanthemi (Erwinaze)	Currently in Shortage
Atropine Sulfate Injection	Currently in Shortage
Atropine Sulfate Ophthalmic Ointment	Currently in Shortage
Azacitidine for Injection	Currently in Shortage
Azithromycin (Azasite) Ophthalmic Solution 1%	Resolved
Azithromycin Tablets	Resolved
Belatacept (Nulojix) Lyophilized Powder for Injection	Currently in Shortage
Bumetanide Injection	Currently in Shortage
Bupivacaine Hydrochloride and Epinephrine Injection	Currently in Shortage
Bupivacaine Hydrochloride Injection	Currently in Shortage
Calcitriol Injection USP 1MCG /ML	Currently in Shortage
Calcium Chloride Injection, USP	Resolved
Calcium Disodium Versenate Injection	Currently in Shortage
Calcium Gluconate Injection	Currently in Shortage
Cefazolin Injection	Currently in Shortage
Cefepime Injection	Resolved
Cefotaxime Sodium Injection	Currently in Shortage
Cefotetan Disodium Injection	Currently in Shortage
Cefoxitin for Injection	Currently in Shortage
Cefoxitin for Injection, USP	Currently in Shortage
Ceftazidime and Avibactam (AVYCAZ®) for Injection, 2 grams/0.5 grams	Currently in Shortage
Ceftolozane and Tazobactam (Zerbaxa) Injection	Currently in Shortage
Chlordiazepoxide Hydrochloride Capsules	Currently in Shortage
Chlorothiazide (Diuril) Oral Suspension	Resolved
Cisatracurium Besylate Injection	Currently in Shortage
Continuous Renal Replacement Therapy (CRRT) Solutions	Currently in Shortage
Cortisone Acetate Tablets	Currently in Shortage
Cyclopentolate Ophthalmic Solution	Currently in Shortage
Cysteamine Hydrochloride Ophthalmic Solution	Currently in Shortage
Cysteine Hydrochloride Injection	Resolved
Deferoxamine Mesylate for Injection, USP	Resolved
Desmopressin Acetate (Stimate) Nasal Spray	Currently in Shortage
Dexamethasone Sodium Phosphate Injection	Currently in Shortage
Dexmedetomidine Injection	Currently in Shortage
Dextrose 25% Injection	Resolved
Dextrose 5% Injection Bags	Resolved
Dextrose 50% Injection	Resolved
Dicyclomine Oral Tablets/Capsules	Resolved
Difluprednate (Durezol) Ophthalmic Emulsion	Resolved
Diltiazem Hydrochloride Injection	Currently in Shortage
Dimercaprol (Bal in Oil) Injection USP	Currently in Shortage
Diphenhydramine Injection	Resolved
Disopyramide Phosphate (Norpace) Capsules	Currently in Shortage
Dobutamine Hydrochloride Injection	Currently in Shortage
Dopamine Hydrochloride Injection	Currently in Shortage
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution	Resolved
Dorzolamide Hydrochloride Ophthalmic Solution	Resolved
Doxycycline Hyclate Injection	Resolved
Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution	Currently in Shortage
Enalaprilat Injection, USP	Currently in Shortage
Epinephrine Injection, 0.1 mg/mL	Currently in Shortage
Epinephrine Injection, Auto-Injector	Currently in Shortage
Erythromycin Lactobionate for Injection, USP	Resolved
Erythromycin Ophthalmic Ointment	Currently in Shortage
Etomidate Injection	Resolved
Famotidine Injection	Currently in Shortage
Famotidine Tablets	Currently in Shortage
Fentanyl Citrate (Sublimaze) Injection	Currently in Shortage
Floxuridine for Injection, USP	Currently in Shortage
Fludrocortisone Acetate Tablets	Resolved
Fluorescein Injection	Resolved
Fluorescein Strips	Currently in Shortage
Flurazepam Hydrochloride Capsules	Resolved
Fluvoxamine ER Capsules	Currently in Shortage
Furosemide Injection	Currently in Shortage
Furosemide Injection, USP	Currently in Shortage
Gemifloxacin Mesylate (Factive) Tablets	Currently in Shortage
Guanfacine Hydrochloride Tablets	Currently in Shortage
Haloperidol Tablets	Resolved
Heparin Sodium and Sodium Chloride 0.9% Injection	Currently in Shortage
Histreline Acetate Implant	Currently in Shortage
Hydralazine Hydrochloride Injection	Currently in Shortage
Hydrocortisone Tablets	Currently in Shortage
Hydrocortisone Tablets, USP	Currently in Shortage
Hydromorphone Hydrochloride Injection	Currently in Shortage
Hydromorphone Hydrochloride Injection, USP	Currently in Shortage
Hydroxocobalamin Injection	Currently in Shortage
Hydroxyprogesterone Caproate Injection	Resolved
Hydroxypropyl (Lacrisert) Cellulose Ophthalmic Insert	Currently in Shortage
Hydroxyzine Pamoate Oral Capsules	Resolved
Imipenem and Cilastatin for Injection	Currently in Shortage
Isoniazid Injection USP	Currently in Shortage
Ketamine Injection	Currently in Shortage
Ketoprofen Capsules	Currently in Shortage
Ketorolac Tromethamine Injection	Currently in Shortage
Labetalol Hydrochloride Injection	Resolved
Letermovir (Prevymis) Injection	Currently in Shortage
Leucovorin Calcium Lyophilized Powder for Injection	Currently in Shortage
Leuprolide Acetate Injection	Currently in Shortage
Levetiracetam Extended-Release Oral Tablets, USP	Resolved
Levetiracetam Immediate-Release Oral Tablets, USP	Resolved
Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags	Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection	Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine	Currently in Shortage
Lithium Oral Solution	Currently in Shortage
Lorazepam Injection	Currently in Shortage
Lorazepam Injection, USP	Currently in Shortage
Loxapine Capsules	Currently in Shortage
Methadone Hydrochloride Injection	Currently in Shortage
Methyldopa Tablets	Currently in Shortage
Metoclopramide Injection, USP	Resolved
Metoprolol Tartrate Injection, USP	Resolved
Metronidazole Injection, USP	Resolved
Midazolam Injection	Currently in Shortage
Midazolam Injection, USP	Currently in Shortage
Misoprostol Tablets	Currently in Shortage
Morphine Sulfate Injection	Currently in Shortage
Multi-Vitamin Infusion (Adult and Pediatric)	Currently in Shortage
Nalbuphine Hydrochloride Injection	Currently in Shortage
Nefazodone Hydrochloride Tablets	Currently in Shortage
Nizatidine Capsules	Currently in Shortage
Ondansetron Hydrochloride Injection	Currently in Shortage
Oxytocin Injection (Synthetic)	Currently in Shortage
Oxytocin Injection, USP Synthetic	Currently in Shortage
Pantoprazole Sodium for Injection	Currently in Shortage
Parathyroid Hormone (Natpara) Injection	Currently in Shortage
Pentamidine Isethionate (Nebupent) For Inhalation Solution	Resolved
Phenytoin Sodium Injection, USP	Resolved
Physostigmine Salicylate Injection, USP	Currently in Shortage
Pindolol Tablets	Currently in Shortage
Potassium Acetate Injection	Currently in Shortage
Potassium Acetate Injection, USP	Currently in Shortage
Prednisolone Acetate 1% Ophthalmic Suspension	Resolved
Procainamide Hydrochloride Injection, USP	Resolved
Progesterone Injection, USP	Resolved
Promethazine (Phenergan) Injection	Currently in Shortage
Propofol Injectable Emulsion	Currently in Shortage
Protamine Sulfate Injection, USP	Currently in Shortage
Rifampin Injection	Currently in Shortage
Rifapentine Tablets	Currently in Shortage
Rocuronium Bromide Injection	Resolved
Ropivacaine Hydrochloride Injection	Currently in Shortage
Sclerosol Intrapleural Aerosol	Currently in Shortage
Scopolamine Transdermal System	Resolved
Sertraline Hydrochloride Oral Solution, USP	Resolved
Sertraline Hydrochloride Tablets	Resolved
Sildenafil Citrate (REVATIO)	Resolved
Sincalide (Kinevac) Lyophilized Powder for Injection	Currently in Shortage
Sodium Acetate Injection	Currently in Shortage
Sodium Bicarbonate Injection	Currently in Shortage
Sodium Chloride 0.9% Injection Bags	Resolved
Sodium Chloride 23.4% Injection	Currently in Shortage
Sodium Chloride Injection USP, 0.9% Vials and Syringes	Currently in Shortage
Sterile Water	Resolved
Succimer (Chemet) Capsules	Currently in Shortage
Sulfasalazine Tablets	Currently in Shortage
Tacrolimus Capsules	Currently in Shortage
Technetium Tc99m Succimer Injection (DMSA)	Currently in Shortage
Teprotumumab-trbw	Currently in Shortage
Thiothixene Capsules	Currently in Shortage
Timolol Maleate Ophthalmic Gel Forming Solution	Currently in Shortage
Timolol Maleate Ophthalmic Solution	Resolved
Timolol Maleate Tablets	Resolved
Tobramycin Lyophilized Powder for Injection	Resolved
Triamcinolone Acetonide (Triesence) Injection, Suspension	Resolved
Triamcinolone Hexacetonide Injectable suspension	Currently in Shortage
Trifluridine Ophthalmic Solution	Resolved
Trimethobenzamide Hydrochloride Capsules	Currently in Shortage
Valproate Sodium Injection	Currently in Shortage
Valproate Sodium Injection, USP	Currently in Shortage
Vecuronium Bromide for Injection	Currently in Shortage
Zinc Acetate Capsules	Currently in Shortage
Zolpidem Tartrate (Edluar) Sublingual Tablets	Resolved

Discontinuations Listed by Generic Name or Active Ingredient

Companies are required under Section 506C of the Federal Food, Drug, and Cosmetic Act (FD&C Act) (as amended by the Food and Drug Administration Safety and Innovation Act) to notify FDA of a permanent discontinuance of certain drug products, six months in advance, or if that is not possible, as soon as practicable. These drugs include those that are life-supporting, life-sustaining or for use in the prevention or treatment of a debilitating disease or condition, including any such drug used in emergency medical care or during surgery. The discontinuations listed on the site reflect information received from manufacturers and are for informational purposes only.

Withdrawal notifications can be found here: https://www.federalregister.gov

Generic Name or Active Ingredient
Abacavir Sulfate and Lamivudine Tablets
Abiraterone Acetate Tablets
Acetaminophen/Tramadol Hydrochloride (Ultracet) Tablets
Acitretin Capsules
Acrivastine and Pseudoephedrine Hydrochloride Capsules
Acyclovir Ointment 5%
Adalimumab (Humira) Pre-filled Syringe
Adapalene/Benzoyl Peroxide Topical Gel
Alfentanil Injection
Amantadine Hydrochloride Capsules
Amiodarone Tablets
Ampicillin for Injection, USP
Anastrozole Tablets
Argatroban Injection
Asenapine (Saphris®) Sublingual Tablets
Asenapine Maleate (Saphris®) Sublingual Tablets
Aspirin/Dipyridamole (Aggrenox) Extended Release Capsules
Atazanavir Capsules
Azithromycin for Injection
Bethanechol Chloride Tablets
Betrixaban (Bevyxxa) Capsules
Budesonide Capsules
Bumetanide Tablets
Busulfan Injection
Capreomycin Injection
Carbidopa, Levodopa and Entacapone, Tablets
Carboplatin Injection
Cardene IV (nicardipine hydrochloride) 0.2 mg/mL in 5% Dextrose
Carisoprodol, Aspirin, and Codeine Phosphate Tablets USP
Caspofungin Acetate Injection
Cefazolin Injection
Cefdinir Capsules
Cefepime Injection
Cefotetan Disodium Injection
Ceftazidime (Fortaz) Injection
Cefuroxime Sodium (Zinacef) Injection
Chlordiazepoxide Hydrochloride USP, Capsules
Cleocin-T 1%
Clindamycin Injection, USP
Clobetasol Propionate Topical Solution 0.05%
Clonazepam Tablets
Clonidine Tablets
Clozapine (FazaClo® ) Orally Disintegrating Tablets
Coumadin Tablets
Dacarbazine for Injection, USP
Darifenacin Hydrobromide Tablets
Dasabuvir Sodium; Ombitasvir; Paritaprevir; Ritonavir (Viekira XR) Tablets
Deferasirox Tablets
Demeclocycline Hydrochloride Tablets, USP
Desogestrel and Ethinyl Estradiol Tablets (ORTHO-CEPT)
Dexmedetomidine Injection
Dexrazoxane Injection
Dextroamphetamine Sulfate Extended-Release Capsules
Diclofenac Sodium Extended Release Tablets
Diclofenac Sodium Topical Gel
Diclofenac Sodium Topical Solution
Didanosine Delayed-Release Capsules USP
Diltiazem Hydrochloride
Diltiazem Hydrochloride Injection
Diphenhydramine Hydrochloride Injection, USP
Disulfiram Tablets
Dobutamine Hydrochloride Injection
Docetaxel Injection
Donepezil Hydrochloride Tablets
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution
Dorzolamide Hydrochloride Ophthalmic Solution
Doxorubicin Hydrochloride Injection
Dutasteride Capsules
Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution
Efavirenz; Emtricitabine; Tenofovir Disoproxil Fumarate (Atripla) Tablets
Enalaprilat Injection, USP
Enoxaparin Sodium Injection
Entecavir Tablets
Eptifibatide (Integrilin) Injection
Ergotamine Tartrate and Caffeine (Cafergot) Tablets
Erlotinib Hydrochloride Tablets
Erythromycin Ethylsuccinate Powder for Suspension
Estradiol (Alora) Patch
Ethacrynic Acid Tablets
Ethambutol Hydrochloride Tablets
Ethinyl Estradiol; Norgestrel Tablets
Etomidate (Amidate) Injection
Etoposide Injection
Exenatide (BYDUREON) Extended Release for Injectable Suspension
Ezetimibe Tablets
Fenoldopam Mesylate (Corlopam) Injection, USP
Fentanyl (Duragesic 100, 12, 25, 37, 50, 75) Extended-Release Film
Finasteride Tablets
Floxuridine for Injection, USP
Fludarabine Phosphate for Injection, USP
Flumazenil Injection
Fluorouracil Injection
Fluoxetine Capsules
Fluoxetine Tablets
Fluticasone Inhalational Powder
Furosemide Tablets
Gemcitabine Hydrochloride Injection
Glipizide Tablets
Glycopyrrolate (Seebri Neohaler) Inhalation Powder
Guanidine Hydrochloride Tablets
Haloperidol Lactate (Haldol) Injection
Haloperidol Lactate Injection
Hydrochlorothiazide and Lisinopril Tablets
Hydrocodone Bitartrate and Homatropine Methylbromide Oral Solution
Hydrocodone/Homatropine Tablets
Hydrocortisone Acetate Suppository
Hydroxychloroquine Sulfate Tablets
Indacterol Maleate (Arcapta Neohaler) Inhalation Powder
Indacterol Maleate and Glycopyrrolate (Utibron Neohaler) Inhalation Powder
Indinavir (CRIXIVAN) Capsules
Indomethacin Capsules
Interferon alfa-2b, Recombinant for Injection
Ipratropium Bromide Inhalation Solution
Isoniazid Tablets
Ketoprofen Capsules
Lamivudine and Zidovudine Tablets
Lamivudine Tablets
Lanoxin (digoxin) Tablets
Levocetirizine Dihydrochloride Tablets
Levofloxacin Tablets
Levoleucovorin Calcium Injection
Lidocaine HCl Topical Jelly
Liothyronine Sodium Tablets
Lisinopril Tablets
Loxapine Capsules
Meclizine Hydrochloride Tablets
Medroxyprogesterone Acetate (Depo-Provera) Injection, Suspension
Medroxyprogesterone Acetate (Provera) Tablet
Mesalamine (CANASA®) Suppositories
Metformin Hydrochloride Extended Release Tablets
Metformin Hydrochloride Tablets
Methocarbamol Tablet, USP
Methotrexate Sodium Injection
Methoxsalen Capsules
Methscopolamine Bromide Tablets
Methylprednisolone Tablets
Metoprolol Tartrate Tablets
Metronidazole (Flagyl) Tablets
Miglitol Tablets
Minocycline Hydrochloride Extended-Release Tablets, USP
Mirtazapine Orally Disintegrating Tablets
Misoprostol Tablets
Montelukast Sodium Chewable Tablet
Montelukast Sodium Tablets
Morphine Sulfate Extended-Release Tablets
Morphine Sulfate Injection, USP
Mycophenolic Acid Delayed Release Tablets
Nadolol Tablets
Nafcillin Sodium Injection
Neomycin Sulfate, Polymyxin B Sulfate and Hydrocortisone Acetate Cream
Neomycin Sulfate, Polymyxin B Sulfate, Bacitracin Zinc and Hydrocortisone Ointment
Nesiritide Powder (NATRECOR) for Injection
Nevirapine (Viramune) Tablets
Nevirapine Extended Release Tablets
Nizatidine Capsules
Norethindrone (NOR QD) Tablets
Norethindrone Acetate/Ethinyl Estradiol (Femhrt) Tablets
Norethindrone Acetate/Ethinyl Estradiol/Ferrous Fumarate Kit
Norethindrone/Ethinyl Estradiol Kit
Nystatin and Triamcinolone Acetonide Topical Cream
Nystatin Topical Cream
Ocriplasmin (Jetrea) Injection
Olanzapine and Fluoxetine (Symbyax) Capsules
Olopatadine Hydrochloride Ophthalmic Solution
Ombitasvir; Paritaprevir; Ritonavir (Technivie) Tablets
Oxalaplatin Injection
Paclitaxel Injection, USP
Paricalcitol Injection
Peginterferon alfa-2b (Sylatron)
Peginterferon alfa-2b Injection
Penicillin V Potassium Tablets
Pentoxifylline Extended-Release Tablets
Phenobarbital Oral Solution
Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets
Pramipexole Dihydrochloride Extended Release Tablets
Pravastatin Sodium (Pravachol) Tablets
Prinivil Tablets
Procardia Capsules
Promethazine Hydrochloride Injection, Solution
Promethazine Suppository
Pyrazinamide Tablets, USP
Rabeprazole Sodium Delayed Release Tablets
Ranitidine Injection, USP
Ranitidine Tablets/Capsules
Ranolazine Extended Release Tablets
Repaglinide Tablets
Rifampin (Rifadin) Capsules
Rifampin Capsules
Rifampin/Isoniazid (Rifamate) Capsules
Rifampin/Isoniazid/Pyrazinamide (Rifater) Tablets
Risedronate Tablets
Risperidone Tablets
Rivastigmine Tartrate Capsules
Rosiglitasone Tablets
Salmeterol Xinafoate Inhalational Powder
Saquinavir Mesylate (Invirase) 200mg Capsules
Simeprevir Capsules
Simvastatin (Zocor) Tablets
Sodium Lactate Injection, USP
Somatropin Recombinant (Humatrope) Injection
Spironolactone Tablets
Stavudine Capsules
Sumatriptan (Sumavel DosePro) Injection
Sumatriptan Succinate (Imitrex) Injection
Sumatriptan Succinate Injection
Talwin (Pentazocine Lactate Injection, USP, CIV)
Telmisartan and Amlodipine (Twynsta) Tablets
Temozolomide (TEMODAR) Capsules
Temozolomide Capsules
Testosterone Topical Gel
Theophylline Extended Release Tablets and Capsules
Tizanidine Hydrochloride Tablets
Tolcapone Tablets
Tositumomab and Iodine I 131 Tositumomab (Bexxar)
Tramadol Hydrochloride (Ultram) Tablets
Trandolapril Tablets
Tranexamic Acid Tablets
Trazodone Tablets
Triamcinolone Acetonide Cream
Triamterene and Hydrochlorothiazide (Dyazide) Capsules
Triamterene and Hydrochlorothiazide Tablets
Trimethobenzamide Hydrochloride Capsules
Ursodiol (Actigall) Capsules
Valacyclovir Tablets
Valsartan Tablets
Vardenafil Hydrochloride Tablets
Vinorelbine Tartrate Injection
Zoledronic Acid Injection
Zolpidem Tartrate Extended Release Tablets