FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

A drug receives Resolved status when the Drug Shortages Staff (DSS) determines that the market is covered, based on information from all manufacturers. The market is considered covered when supply is available from at least one manufacturer to cover total market demand. However, some manufacturers may not have all presentations available. DSS monitors the supply of products with Resolved status. For the most current supply information, contact the manufacturers.

Generic Name or Active Ingredient Status
Acetazolamide Injection Currently in Shortage
Amifostine Injection Currently in Shortage
Amino Acids Currently in Shortage
Amoxapine Tablets Currently in Shortage
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets Currently in Shortage
Anagrelide Hydrochloride Capsules Resolved
Atropine Sulfate Injection Currently in Shortage
Atropine Sulfate Ophthalmic Ointment Resolved
Azacitidine for Injection Currently in Shortage
Azithromycin (Azasite) Ophthalmic Solution 1% Resolved
Belatacept (Nulojix) Lyophilized Powder for Injection Currently in Shortage
Bumetanide Injection Currently in Shortage
Bupivacaine Hydrochloride and Epinephrine Injection Currently in Shortage
Bupivacaine Hydrochloride Injection Currently in Shortage
Calcitriol Injection 1MCG/ML Resolved
Calcium Disodium Versenate Injection Currently in Shortage
Calcium Gluconate Injection Currently in Shortage
Cefazolin Injection Currently in Shortage
Cefotaxime Sodium Injection Currently in Shortage
Cefotetan Disodium Injection Currently in Shortage
Cefoxitin for Injection Currently in Shortage
Ceftazidime and Avibactam (AVYCAZ®) for Injection, 2 grams/0.5 grams Currently in Shortage
Ceftolozane and Tazobactam (Zerbaxa) Injection Currently in Shortage
Chlordiazepoxide Hydrochloride Capsules Currently in Shortage
Chloroprocaine Hydrochloride Injection Currently in Shortage
Cisatracurium Besylate Injection Resolved
Continuous Renal Replacement Therapy (CRRT) Solutions Currently in Shortage
Cortisone Acetate Tablets Currently in Shortage
Cyclopentolate Ophthalmic Solution Currently in Shortage
Cysteamine Hydrochloride Ophthalmic Solution Currently in Shortage
Cysteine Hydrochloride Injection Resolved
Cytarabine Injection Currently in Shortage
Deferoxamine Mesylate for Injection, USP Resolved
Desmopressin Acetate Nasal Spray Currently in Shortage
Dexamethasone Sodium Phosphate Injection Currently in Shortage
Dexmedetomidine Injection Currently in Shortage
Dextrose 5% Injection Bags Resolved
Difluprednate (Durezol) Ophthalmic Emulsion Resolved
Digoxin Injection Currently in Shortage
Diltiazem Hydrochloride Injection Currently in Shortage
Dimercaprol (Bal in Oil) Injection Resolved
Disopyramide Phosphate (Norpace) Capsules Currently in Shortage
Dobutamine Hydrochloride Injection Currently in Shortage
Dopamine Hydrochloride Injection Currently in Shortage
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution Resolved
Dorzolamide Hydrochloride Ophthalmic Solution Resolved
Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution Currently in Shortage
Enalaprilat Injection Currently in Shortage
Epinephrine Injection, 0.1 mg/mL Currently in Shortage
Epinephrine Injection, Auto-Injector Currently in Shortage
Erythromycin Ophthalmic Ointment Resolved
Etomidate Injection Resolved
Famotidine Injection Currently in Shortage
Famotidine Tablets Currently in Shortage
Fentanyl Citrate (Sublimaze) Injection Currently in Shortage
Floxuridine for Injection Currently in Shortage
Fludrocortisone Acetate Tablets Resolved
Fluorescein Strips Resolved
Fluvoxamine ER Capsules Currently in Shortage
Furosemide Injection Currently in Shortage
Gemifloxacin Mesylate (Factive) Tablets Currently in Shortage
Gentamicin Sulfate Injection Currently in Shortage
Guanfacine Hydrochloride Tablets Currently in Shortage
Haloperidol Tablets Resolved
Heparin Sodium and Sodium Chloride 0.9% Injection Currently in Shortage
Hydralazine Hydrochloride Injection Resolved
Hydrocortisone Tablets Currently in Shortage
Hydromorphone Hydrochloride Injection Currently in Shortage
Hydroxocobalamin Injection Currently in Shortage
Hydroxyprogesterone Caproate Injection Resolved
Hydroxypropyl (Lacrisert) Cellulose Ophthalmic Insert Currently in Shortage
Hydroxyzine Pamoate Oral Capsules Resolved
Imipenem and Cilastatin for Injection Currently in Shortage
Isoniazid Injection Currently in Shortage
Ketamine Injection Currently in Shortage
Ketoprofen Capsules Currently in Shortage
Ketorolac Tromethamine Injection Currently in Shortage
Kit for the Preparation of Technetium Tc 99m Sulfur Colloid Injection Currently in Shortage
Letermovir (Prevymis) Injection Resolved
Leucovorin Calcium Lyophilized Powder for Injection Currently in Shortage
Leuprolide Acetate Injection Currently in Shortage
Levetiracetam Extended-Release Oral Tablets, USP Resolved
Levetiracetam Immediate-Release Oral Tablets, USP Resolved
Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine Currently in Shortage
Lithium Oral Solution Currently in Shortage
Lorazepam Injection Currently in Shortage
Loxapine Capsules Currently in Shortage
Mannitol Injection Currently in Shortage
Mepivacaine Hydrochloride Injection Currently in Shortage
Methadone Hydrochloride Injection Resolved
Methohexital Sodium (Brevital) Injection Currently in Shortage
Methyldopa Tablets Currently in Shortage
Metoclopramide Injection, USP Resolved
Midazolam Injection Currently in Shortage
Misoprostol Tablets Currently in Shortage
Morphine Sulfate Injection Currently in Shortage
Multi-Vitamin Infusion (Adult and Pediatric) Currently in Shortage
Nalbuphine Hydrochloride Injection Resolved
Nefazodone Hydrochloride Tablets Currently in Shortage
Nizatidine Capsules Currently in Shortage
Ondansetron Hydrochloride Injection Currently in Shortage
Oxytocin Injection (Synthetic) Resolved
Paclitaxel Injection (protein-bound particles) Currently in Shortage
Pantoprazole Sodium for Injection Currently in Shortage
Parathyroid Hormone (Natpara) Injection Currently in Shortage
Pentamidine Isethionate (Nebupent) For Inhalation Solution Resolved
Phenytoin Sodium Injection, USP Resolved
Physostigmine Salicylate Injection Currently in Shortage
Pindolol Tablets Currently in Shortage
Potassium Acetate Injection Currently in Shortage
Prednisolone Acetate 1% Ophthalmic Suspension Resolved
Progesterone Injection, USP Resolved
Promethazine (Phenergan) Injection Currently in Shortage
Propofol Injectable Emulsion Currently in Shortage
Protamine Sulfate Injection Currently in Shortage
Rifampin Injection Currently in Shortage
Rifapentine Tablets Currently in Shortage
Rocuronium Bromide Injection Resolved
Ropivacaine Hydrochloride Injection Currently in Shortage
Sclerosol Intrapleural Aerosol Currently in Shortage
Scopolamine Transdermal System Resolved
Sertraline Hydrochloride Oral Solution, USP Resolved
Sertraline Hydrochloride Tablets Resolved
Sildenafil Citrate (REVATIO) Resolved
Sincalide (Kinevac) Lyophilized Powder for Injection Currently in Shortage
Sodium Acetate Injection Currently in Shortage
Sodium Bicarbonate Injection Currently in Shortage
Sodium Chloride 0.9% Injection Bags Resolved
Sodium Chloride 23.4% Injection Currently in Shortage
Sodium Chloride Injection USP, 0.9% Vials and Syringes Currently in Shortage
Sodium Phosphates Injection Currently in Shortage
Sterile Water Resolved
Succimer (Chemet) Capsules Resolved
Sulfasalazine Tablets Currently in Shortage
Tacrolimus Capsules Currently in Shortage
Technetium Tc99m Succimer Injection (DMSA) Currently in Shortage
Teprotumumab-trbw Currently in Shortage
Thiothixene Capsules Currently in Shortage
Timolol Maleate Ophthalmic Gel Forming Solution Resolved
Timolol Maleate Ophthalmic Solution Resolved
Tobramycin Lyophilized Powder for Injection Resolved
Tocilizumab Injection Currently in Shortage
Triamcinolone Acetonide Injectable Suspension Currently in Shortage
Triamcinolone Hexacetonide Injectable suspension Currently in Shortage
Trimethobenzamide Hydrochloride Capsules Currently in Shortage
Valproate Sodium Injection Currently in Shortage
Varenicline Tartrate (Chantix) Tablets Currently in Shortage
Vecuronium Bromide for Injection Currently in Shortage
Zinc Acetate Capsules Resolved
Zolpidem Tartrate (Edluar) Sublingual Tablets Resolved

Discontinuations Listed by Generic Name or Active Ingredient

Companies are required under Section 506C of the Federal Food, Drug, and Cosmetic Act (FD&C Act) (as amended by the Food and Drug Administration Safety and Innovation Act) to notify FDA of a permanent discontinuance of certain drug products, six months in advance, or if that is not possible, as soon as practicable. These drugs include those that are life-supporting, life-sustaining or for use in the prevention or treatment of a debilitating disease or condition, including any such drug used in emergency medical care or during surgery. The discontinuations listed on the site reflect information received from manufacturers and are for informational purposes only.

Withdrawal notifications can be found here: https://www.federalregister.gov

Generic Name or Active Ingredient
Abacavir Sulfate and Lamivudine Tablets
Abiraterone Acetate Tablets
Acitretin Capsules
Acrivastine and Pseudoephedrine Hydrochloride Capsules
Acyclovir Ointment 5%
Adalimumab (Humira) Pre-filled Syringe
Adapalene/Benzoyl Peroxide Topical Gel
Albuterol Sulfate Aerosol, Metered
Alprostadil Suppository
Aluminum Hydroxide and Magnesium Carbonate (Gaviscon Regular Strength)
Amantadine Hydrochloride Capsules
Amiodarone Tablets
Amitriptyline Hydrochloride Tablets
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets
Ampicillin for Injection
Ampicillin for Injection, USP
Asenapine (Saphris®) Sublingual Tablets
Asenapine Maleate (Saphris®) Sublingual Tablets
Aspirin/Dipyridamole (Aggrenox) Extended Release Capsules
Atazanavir Capsules
Azithromycin for Injection
Bacitracin Ophthalmic Ointment
Benzonatate Capsules
Budesonide Capsules
Bumetanide Tablets
Busulfan Injection
Capreomycin Injection
Captopril Tablets
Captopril/Hydrochlorothiazide Tablets
Carbidopa, Levodopa and Entacapone, Tablets
Carboplatin Injection
Cardene IV (nicardipine hydrochloride) 0.2 mg/mL in 5% Dextrose
Carisoprodol, Aspirin, and Codeine Phosphate Tablets USP
Caspofungin Acetate Injection
Cefazolin Injection
Cefdinir Capsules
Cefotetan Disodium Injection
Ceftazidime (Fortaz) Injection
Cefuroxime Sodium (Zinacef) Injection
Chlordiazepoxide Hydrochloride USP, Capsules
Cleocin-T 1%
Clindamycin and Benzoyl Peroxide Gel, 1%/5%
Clindamycin Injection
Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2%/5%
Clindamycin Phosphate Topical Solution 1%
Clobetasol Propionate Ointment 0.05%
Clobetasol Propionate Topical Solution 0.05%
Clonazepam Tablets
Clonidine Tablets
Clozapine (FazaClo® ) Orally Disintegrating Tablets
Cytarabine Injection
Cytotec (Misoprostol) Tablets
Dacarbazine for Injection, USP
Daptomycin Injection
Darifenacin Hydrobromide Tablets
Dasabuvir Sodium; Ombitasvir; Paritaprevir; Ritonavir (Viekira XR) Tablets
Deferasirox Tablets
Desogestrel and Ethinyl Estradiol Tablets (ORTHO-CEPT)
Dextroamphetamine Sulfate Extended-Release Capsules
Diclofenac Sodium Extended Release Tablets
Diclofenac Sodium Topical Solution
Didanosine Delayed-Release Capsules USP
Diflorasone Diacetate Ointment, 0.05%
Diltiazem Hydrochloride Injection
Diphenhydramine Hydrochloride Injection, USP
Disulfiram Tablets
Docetaxel Injection
Dofetilide Capsules
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution
Dorzolamide Hydrochloride Ophthalmic Solution
Efavirenz; Emtricitabine; Tenofovir Disoproxil Fumarate (Atripla) Tablets
Enoxaparin Sodium Injection
Eptifibatide (Integrilin) Injection
Ergotamine Tartrate and Caffeine (Cafergot) Tablets
Erlotinib Hydrochloride Tablets
Erythromycin Ethylsuccinate Powder for Suspension
Esomeprazole Sodium for Injection
Estradiol (Alora) Patch
Ethacrynic Acid Tablets
Ethambutol Hydrochloride Tablets
Etoposide Injection
Exenatide (BYDUREON) Extended Release for Injectable Suspension
Fenoldopam Mesylate (Corlopam) Injection, USP
Finasteride Tablets
Floxuridine for Injection, USP
Flumazenil Injection
Fluocinonide Gel 0.05%
Fluocinonide Ointment 0.05%
Fluocinonide Topical Solution
Fluorometholone Ophthalmic Ointment
Fluoxetine Capsules
Fluoxetine Tablets
Fluticasone Inhalational Powder
Fosphenytoin Sodium Injection
Furosemide Tablets
Gemcitabine Hydrochloride Injection
Gentamicin Sulfate and Prednisolone Acetate Ophthalmic Ointment
Glipizide Tablets
Guanidine Hydrochloride Tablets
Haloperidol Lactate (Haldol) Injection
Haloperidol Lactate Injection
Histrelin Acetate Implant
Hydrochlorothiazide and Lisinopril Tablets
Hydrocodone Bitartrate and Homatropine Methylbromide Oral Solution
Hydrocodone/Homatropine Tablets
Hydrocortisone Acetate Suppository
Hydroxychloroquine Sulfate Tablets
Indinavir (CRIXIVAN) Capsules
Indomethacin Capsules
Interferon alfa-2b, Recombinant for Injection
Iopamidol (Isovue) Injection
Ipratropium Bromide Inhalation Solution
Isoniazid Tablets
Ketoprofen Capsules
Lamivudine and Tenofovir Disoproxil Fumarate Tablets
Lamivudine and Zidovudine Tablets
Lamivudine Tablets
Lanoxin (digoxin) Tablets
Lidocaine HCl Topical Jelly
Liothyronine Sodium Tablets
Lisinopril Tablets
Loxapine Capsules
Meclizine Hydrochloride Tablets
Medroxyprogesterone Acetate (Depo-Provera) Injection, Suspension
Mesalamine (CANASA®) Suppositories
Metformin Hydrochloride Extended Release Tablets
Methocarbamol Tablet, USP
Methoxsalen Capsules
Methyldopa Tablets
Methylprednisolone Tablets
Metoclopramide Tablets
Metoprolol Tartrate Tablets
Metronidazole (Flagyl) Tablets
Miglitol Tablets
Mirtazapine Orally Disintegrating Tablets
Mometasone Furoate Monohydrate Nasal Spray
Montelukast Sodium Chewable Tablet
Montelukast Sodium Tablets
Morphine Sulfate Extended-Release Tablets
Moxifloxacin (Moxeza) Ophthalmic Solution
Nadolol Tablets
Nafcillin Sodium Injection
Neomycin Sulfate, Polymyxin B Sulfate and Hydrocortisone Acetate Cream
Neomycin Sulfate, Polymyxin B Sulfate, Bacitracin Zinc and Hydrocortisone Ointment
Nesiritide Powder (NATRECOR) for Injection
Nevirapine (Viramune) Tablets
Nevirapine Oral Suspension
Norethindrone (NOR QD) Tablets
Norethindrone Acetate/Ethinyl Estradiol (Femhrt) Tablets
Norethindrone Acetate/Ethinyl Estradiol/Ferrous Fumarate Kit
Norethindrone/Ethinyl Estradiol Kit
Nystatin and Triamcinolone Acetonide Topical Cream
Nystatin Topical Cream
Olanzapine and Fluoxetine (Symbyax) Capsules
Olopatadine Hydrochloride Ophthalmic Solution
Ombitasvir; Paritaprevir; Ritonavir (Technivie) Tablets
Ondansetron Hydrochloride Injection
Oxalaplatin Injection
Paclitaxel Injection, USP
Paricalcitol Injection
Peginterferon alfa-2b (Sylatron)
Peginterferon alfa-2b Injection
Pentoxifylline Extended-Release Tablets
Phenobarbital Oral Solution
Piroxicam Capsules
Pravastatin Sodium (Pravachol) Tablets
Procardia Capsules
ProHance® (Gadoteridol) Injection
Promethazine Hydrochloride Injection, Solution
Rabeprazole Sodium Delayed Release Tablets
Ranolazine Extended Release Tablets
Repaglinide Tablets
Rifampin (Rifadin) Capsules
Rifampin Capsules
Rifampin/Isoniazid (Rifamate) Capsules
Rifampin/Isoniazid/Pyrazinamide (Rifater) Tablets
Risedronate Tablets
Risperidone Tablets
Rosiglitasone Tablets
Salmeterol Xinafoate Inhalational Powder
Saquinavir Mesylate (Invirase) 200mg Capsules
Simeprevir Capsules
Simvastatin (Zocor) Tablets
Simvastatin Tablets
Somatropin Recombinant (Humatrope) Injection
Spironolactone Tablets
Stavudine Capsules
Sulfacetamide Sodium and Prednisolone Acetate Ophthalmic Ointment
Sumatriptan (Sumavel DosePro) Injection
Sumatriptan Succinate Injection
Talwin (Pentazocine Lactate Injection, USP, CIV)
Telmisartan and Amlodipine (Twynsta) Tablets
Temozolomide Capsules
Tipranavir Oral Solution
Tizanidine Hydrochloride Capsules
Tizanidine Hydrochloride Tablets
Tolcapone Tablets
Trandolapril Tablets
Tranexamic Acid Tablets
Triamcinolone Acetonide Cream
Triamterene and Hydrochlorothiazide (Dyazide) Capsules
Triamterene and Hydrochlorothiazide Tablets
Trimethobenzamide Hydrochloride Capsules
Ursodiol (Actigall) Capsules
Valacyclovir Tablets
Vancomycin Hydrochloride for Injection
Vardenafil Hydrochloride Tablets
Vinorelbine Tartrate Injection

Analgesia/Addiction

Anesthesia

Anti-Infective

Antiviral

Cardiovascular

Dental

  • This category is empty.
  • Dermatology

    Endocrinology/Metabolism

    Gastroenterology

    Hematology

    Inborn Errors

  • This category is empty.
  • Medical Imaging

    Musculoskeletal

    Neurology

    Oncology

    Ophthalmology

    Other

    Pediatric

    Psychiatry

    Pulmonary/Allergy

    Renal

    Reproductive

    Rheumatology

    Total Parenteral Nutrition

    Transplant

    Urology

    New

    October 15, 2021

    October 13, 2021

    October 12, 2021

    October 08, 2021

    October 07, 2021

    Updated

    October 13, 2021

    October 12, 2021

    October 08, 2021

    October 07, 2021

    October 06, 2021

    Note: If you need help accessing information in different file formats, see Instructions for Downloading Viewers and Players.
    Language Assistance Available: Español | 繁體中文 | Tiếng Việt | 한국어 | Tagalog | Русский | العربية | Kreyòl Ayisyen | Français | Polski | Português | Italiano | Deutsch | 日本語 | فارسی | English