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TPLC - Total Product Life Cycle
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Device powered laser surgical instrument
Definition A laser (light amplification by stimulated emission of radiation) based device having coherence, collimated and typically monochromatic radiation. Typically indicated to to cut, destroy, remove or coagulate tissue, generally soft tissue, for general surgical purpose in medical specialties of general and plastic surgery, dermatology/aesthetic, podiatry, otolaryngology (ent), gynecology, neurosurgery, orthopedics (soft tissue), dental and oral surgery, and dentistry. The classification regulation 21 cfr 878.4810 describes a device that is carbon dioxide or argon laser intended to cut, destroy, remove or coagulate tissue by the light.
Product CodeGEX
Regulation Number 878.4810
Device Class 2


Premarket Reviews
ManufacturerDecision
A.R.C. LASER GMBH
  SUBSTANTIALLY EQUIVALENT 2
ACCLARO CORPORATION
  SUBSTANTIALLY EQUIVALENT 1
ACCURE ACNE, INC.
  SUBSTANTIALLY EQUIVALENT 1
AESTHETIC TECHNOLOGY LTD
  SUBSTANTIALLY EQUIVALENT 1
AESTHETIC TECHNOLOGY LTD.
  SUBSTANTIALLY EQUIVALENT 1
ALCON LABORATORIES, INC.
  SUBSTANTIALLY EQUIVALENT 1
ALLENGERS GLOBAL HEALTHCARE PRIVATE LIMITED
  SUBSTANTIALLY EQUIVALENT 1
ALMA LASERS INC.
  SUBSTANTIALLY EQUIVALENT 2
ALMA LASERS, INC.
  SUBSTANTIALLY EQUIVALENT 2
ALMA LASERS, LTD.
  SUBSTANTIALLY EQUIVALENT 2
AMI INC.
  SUBSTANTIALLY EQUIVALENT 1
AMT ENGINEERING CO., LTD
  SUBSTANTIALLY EQUIVALENT 2
ANGIODYNAMICS, INC.
  SUBSTANTIALLY EQUIVALENT 1
ASCLEPION LASER TECHNOLOGIES GMBH
  SUBSTANTIALLY EQUIVALENT 6
AVAVA, INC
  SUBSTANTIALLY EQUIVALENT 1
AVENDA HEALTH, INC.
  SUBSTANTIALLY EQUIVALENT 1
AZENA MEDICAL, LLC
  SUBSTANTIALLY EQUIVALENT 1
BEIJING ADSS DEVELOPMENT CO., LTD.
  SUBSTANTIALLY EQUIVALENT 2
BEIJING GLOBALIPL DEVELOPMENT CO., LTD.
  SUBSTANTIALLY EQUIVALENT 2
BEIJING HUACHENG TAIKE TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
BEIJING KES BIOLOGY TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 2
BEIJING LASERTELL MEDICAL CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
BEIJING LEAD BEAUTY S & T CO., LTD
  SUBSTANTIALLY EQUIVALENT 2
BEIJING MEGA BEAUTY TECHNOLOGY CO.,LTD.
  SUBSTANTIALLY EQUIVALENT 1
BEIJING SANO LASER S&T DEVELOPMENT CO., LTD
  SUBSTANTIALLY EQUIVALENT 2
BEIJING SEA HEART INTERNATIONAL SCIENCE AND TECHNOLOGYCO.LTD
  SUBSTANTIALLY EQUIVALENT 1
BEIJING STAR NEW TECH CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
BEIJING STELLE LASER TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
BEIJING SUPERLASER TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 3
BEIJING UNT TECHNOLOGY CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
BEIJING UNT TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
BIO-MED USA INC
  SUBSTANTIALLY EQUIVALENT 2
BIOLASE, INC
  SUBSTANTIALLY EQUIVALENT 1
BIOLASE, INC.
  SUBSTANTIALLY EQUIVALENT 3
BIOS S.R.L.
  SUBSTANTIALLY EQUIVALENT 1
BIOTEC ITALIA, SRL
  SUBSTANTIALLY EQUIVALENT 1
BLUECORE COMPANY CO LTD
  SUBSTANTIALLY EQUIVALENT 1
BOSTON SCIENTIFIC
  SUBSTANTIALLY EQUIVALENT 1
BT BEAMEDICAL TACHNOOGIES LTD. (BEAMED)
  SUBSTANTIALLY EQUIVALENT 1
CANADIAN PIONEER MEDICAL TECHNOLOGY CORPORATION
  SUBSTANTIALLY EQUIVALENT 3
CANADIAN PIONEER MEDICAL TECHNOLOGY CORPORATION (CPMT LASER)
  SUBSTANTIALLY EQUIVALENT 2
CANDELA CORP.
  SUBSTANTIALLY EQUIVALENT 1
CANDELA CORPORATION
  SUBSTANTIALLY EQUIVALENT 5
CAO GROUP, INC.
  SUBSTANTIALLY EQUIVALENT 3
CERAMOPTEC GMBH
  SUBSTANTIALLY EQUIVALENT 1
CLINICAL LASERTHERMIA SYSTEMS, AB
  SUBSTANTIALLY EQUIVALENT 1
CONVERGENT LASER TECHNOLOGIES
  SUBSTANTIALLY EQUIVALENT 1
CPMT LASER (CANADIAN PIONEER MEDICAL TECHNOLOGY CORPORATION)
  SUBSTANTIALLY EQUIVALENT 1
CUTERA, INC.
  SUBSTANTIALLY EQUIVALENT 3
CYNOSURE LLC
  SUBSTANTIALLY EQUIVALENT 2
CYNOSURE, LLC.
  SUBSTANTIALLY EQUIVALENT 1
D.E.A PROJECT S.R.1.
  SUBSTANTIALLY EQUIVALENT 1
DAEJU MEDITECH ENGINEERING CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
DAESHIN ENTERPRISE CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
DORNIERMEDTECH AMERICA, INC
  SUBSTANTIALLY EQUIVALENT 1
EL. EN ELECTRONIC ENGINEERING SPA
  SUBSTANTIALLY EQUIVALENT 1
EL. EN. S.P.A.
  SUBSTANTIALLY EQUIVALENT 1
EL..EN. ELECTRONIC ENGINEERING SPA
  SUBSTANTIALLY EQUIVALENT 1
EL.EN ELECTROINC ENGINEERING SPA
  SUBSTANTIALLY EQUIVALENT 1
EL.EN ELECTRONIC ENGINEERING SPA
  SUBSTANTIALLY EQUIVALENT 3
EL.EN. ELECTRONIC ENGINEERING SPA
  SUBSTANTIALLY EQUIVALENT 1
EL.EN. S.P.A.
  SUBSTANTIALLY EQUIVALENT 5
ELESTA SPA
  SUBSTANTIALLY EQUIVALENT 2
ELLIPSE A/S
  SUBSTANTIALLY EQUIVALENT 1
EMOLED, SRL
  SUBSTANTIALLY EQUIVALENT 1
ENAMEL PURE
  SUBSTANTIALLY EQUIVALENT 1
ENDYMED MEDICAL, LTD.
  SUBSTANTIALLY EQUIVALENT 1
EPILADY 2000 LLC
  SUBSTANTIALLY EQUIVALENT 2
FA INTERNATIONAL, LP
  SUBSTANTIALLY EQUIVALENT 1
FOTONA D.O.O.
  SUBSTANTIALLY EQUIVALENT 10
GLOBAL MED SYSTEMS SL
  SUBSTANTIALLY EQUIVALENT 1
GME GERMAN MEDICAL ENGINEERING GMBH
  SUBSTANTIALLY EQUIVALENT 3
GUANGZHOU CHUANG ZAO MEI TECHNOLOGY CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
GYRUS ACMI, INC.
  SUBSTANTIALLY EQUIVALENT 2
HEBEI ZHEMAI TECHNOLOGY CO., LTD
  SUBSTANTIALLY EQUIVALENT 2
HIGH TECHNOLOGY PRODUCTS SLU
  SUBSTANTIALLY EQUIVALENT 3
HIRONIC CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
HULASER, INC.
  SUBSTANTIALLY EQUIVALENT 1
I.T.S. GROUP S.R.L.
  SUBSTANTIALLY EQUIVALENT 1
IDS, LIMITED
  SUBSTANTIALLY EQUIVALENT 1
IDS, LTD.
  SUBSTANTIALLY EQUIVALENT 1
ILOODA CO LTD
  SUBSTANTIALLY EQUIVALENT 2
ILOODA CO,.LTD.
  SUBSTANTIALLY EQUIVALENT 2
ILOODA CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
INMODE LTD.
  SUBSTANTIALLY EQUIVALENT 1
INNOVAQUARTZ LLC
  SUBSTANTIALLY EQUIVALENT 2
INNOVOYCE
  SUBSTANTIALLY EQUIVALENT 1
INNOVOYCE LLC
  SUBSTANTIALLY EQUIVALENT 1
INWOUND APS
  SUBSTANTIALLY EQUIVALENT 1
IPG MEDICAL
  SUBSTANTIALLY EQUIVALENT 1
IPG MEDICAL CORPORATION
  SUBSTANTIALLY EQUIVALENT 1
IVYLASER (BEIJING) TECHNOLOGY CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
JEISYS MEDICAL INC
  SUBSTANTIALLY EQUIVALENT 2
KARL STORZ SE & CO. KG
  SUBSTANTIALLY EQUIVALENT 1
LASER ENGINEERING, INC.
  SUBSTANTIALLY EQUIVALENT 1
LASEROPTEK CO., LTD.
  SUBSTANTIALLY EQUIVALENT 7
LEASEIR TECHNOLOGIES S.L.U.
  SUBSTANTIALLY EQUIVALENT 1
LEONI FIBER OPTICS, INC.
  SUBSTANTIALLY EQUIVALENT 1
LIGHTSCALPEL INC
  SUBSTANTIALLY EQUIVALENT 1
LIGHTSENSE TECHNOLOGIES LTD
  SUBSTANTIALLY EQUIVALENT 1
LISA LASER PRODUCTS GMBH
  SUBSTANTIALLY EQUIVALENT 1
LMG LASERS COMERCIO, IMPORTACAO E EXPORTACAO LTDA
  SUBSTANTIALLY EQUIVALENT 1
LOTUXS MEDTECH (SUZHOU) CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
LUMENIS BE LTD.
  SUBSTANTIALLY EQUIVALENT 2
LUMENIS BE, LTD.
  SUBSTANTIALLY EQUIVALENT 1
LUMENIS INC.
  SUBSTANTIALLY EQUIVALENT 1
LUMENIS LTD.
  SUBSTANTIALLY EQUIVALENT 4
LUMENIS, LTD.
  SUBSTANTIALLY EQUIVALENT 1
LUTRONIC CORPORATION
  SUBSTANTIALLY EQUIVALENT 3
LUTRONIC GLOBAL
  SUBSTANTIALLY EQUIVALENT 1
LUVO MEDICAL TECHNOLOGIES, INC
  SUBSTANTIALLY EQUIVALENT 3
M&T S.R.L.
  SUBSTANTIALLY EQUIVALENT 1
M&T SRL
  SUBSTANTIALLY EQUIVALENT 2
MEDICAL SAN INDÚSTRIA DE EQUIPAMENTOS MÉDICOS LTDA
  SUBSTANTIALLY EQUIVALENT 1
MEDICAL SAN INDÚSTRIA DE EQUIPAMENTOS MÉDICOS LTDA.
  SUBSTANTIALLY EQUIVALENT 1
MEDICO USA INC.
  SUBSTANTIALLY EQUIVALENT 1
MEDICREATIONS LLC
  SUBSTANTIALLY EQUIVALENT 1
MEDMIX CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
MEGABAY S.A.
  SUBSTANTIALLY EQUIVALENT 1
MILLENNIUM DENTAL TECHNOLOGIES, INC.
  SUBSTANTIALLY EQUIVALENT 1
MONTERIS MEDICAL
  SUBSTANTIALLY EQUIVALENT 2
MONTERIS MEDICAL,
  SUBSTANTIALLY EQUIVALENT 1
MONTERIS MEDICAL, INC.
  SUBSTANTIALLY EQUIVALENT 1
NANOSPECTRA BIOSCIENCES, INC.
  SUBSTANTIALLY EQUIVALENT 1
NEAUVIA NORTH AMERICA
  SUBSTANTIALLY EQUIVALENT 2
OLYMPUS SURGICAL TECHNOLOGIES AMERICA
  SUBSTANTIALLY EQUIVALENT 2
OMNI-GUIDE HOLDINGS, INC.
  SUBSTANTIALLY EQUIVALENT 2
OMNIGUIDE, INC.
  SUBSTANTIALLY EQUIVALENT 2
QUANTA SYSTEM SPA
  SUBSTANTIALLY EQUIVALENT 11
QUANTA SYSTEM, S.P.A
  SUBSTANTIALLY EQUIVALENT 1
QUANTA SYSTEM, S.P.A.
  SUBSTANTIALLY EQUIVALENT 2
QUANTEL MEDICAL
  SUBSTANTIALLY EQUIVALENT 1
RAJA TRADING COMPANY, INC.
  SUBSTANTIALLY EQUIVALENT 2
REALTON (SUZHOU) MEDICAL TECHNOLOGY CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
REALTON (SUZHOU) MEDICAL TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 2
REVEALLUX, CORP
  SUBSTANTIALLY EQUIVALENT 1
RHEIN LASER TECHNOLOGIES CO., LTD.
  SUBSTANTIALLY EQUIVALENT 2
ROHRER AESTHETICS
  SUBSTANTIALLY EQUIVALENT 1
ROHRER AESTHETICS, LLC
  SUBSTANTIALLY EQUIVALENT 3
SAN HE LEFIS ELECTRONICS CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
SANHE LASERCONN TECH CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
SCITON, INC
  SUBSTANTIALLY EQUIVALENT 3
SENTIENT MANUFACTURING LLC
  SUBSTANTIALLY EQUIVALENT 1
SHANGDONG HUAMEI TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 3
SHANGHAI APOLO MEDICAL TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 7
SHANGHAI BELE MEDICAL TECHNOLOGY CO.,LTD
  SUBSTANTIALLY EQUIVALENT 2
SHANGHAI OMNI LASER SKINOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 2
SHANGHAI WONDERFUL OPTO-ELECTRICS TECH. CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
SHARPLIGHT TECHNOLOGIES LTD
  SUBSTANTIALLY EQUIVALENT 1
SHENZHEN GSD TECH CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
SHENZHEN GSD TECH CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
SHENZHEN LEAFLIFE TECHNOLOGY CO., LTD
  SUBSTANTIALLY EQUIVALENT 2
SHENZHENSHI SINCOHEREN S&T DEVELOPMENT CO.,LTD.
  SUBSTANTIALLY EQUIVALENT 1
SILHOUET-TONE CORPORATION
  SUBSTANTIALLY EQUIVALENT 1
SMEDTRUM MEDICAL TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 3
SNJ CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
SNJ CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
SOLITON INC.
  SUBSTANTIALLY EQUIVALENT 5
SOLTA MEDICAL
  SUBSTANTIALLY EQUIVALENT 1
SOLTA MEDICAL, INC.
  SUBSTANTIALLY EQUIVALENT 1
SQUALUS MED LTD.
  SUBSTANTIALLY EQUIVALENT 1
STRATA SKIN SCIENCES, INC.
  SUBSTANTIALLY EQUIVALENT 1
SUN PHARMACEUTICAL INDUSTRIES, INC.
  SUBSTANTIALLY EQUIVALENT 1
TERMOSALUD
  SUBSTANTIALLY EQUIVALENT 2
THERALASER MEDTECH (CHINA) CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
TRIANGEL RSD LIMITED
  SUBSTANTIALLY EQUIVALENT 1
VENUS CONCEPT USA INC.
  SUBSTANTIALLY EQUIVALENT 1
VYDENCE MEDICAL INDUSTRIA E COMERCIO LTDA
  SUBSTANTIALLY EQUIVALENT 3
W & R INVESTMENTS, LLC DBA LASER ENGINEERING
  SUBSTANTIALLY EQUIVALENT 1
WEIFANG DRAGONFLY ELECTRONICS TECHNOLOGY CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
WEIFANG KM ELECTRONICS CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
WEIFANG MINGLIANG ELECTRONICS CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
WINGDERM ELECTRO-OPTICS LTD.
  SUBSTANTIALLY EQUIVALENT 1
WON TECH CO., LTD.
  SUBSTANTIALLY EQUIVALENT 11
WONTECH CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
WUHAN DIMED LASER TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
WUHAN LOTUXS TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 2
WUHAN PIOON TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 2
WUHAN PIOON TECHNOLOGY CO.,LTD.
  SUBSTANTIALLY EQUIVALENT 3
XUZHOU KERNEL MEDICAL EQUIPMENT CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
YASSEN WELLNESS LLC
  SUBSTANTIALLY EQUIVALENT 1
ZELTIQ AESTHETICS INC.
  SUBSTANTIALLY EQUIVALENT 1
ZELTIQ AESTHETICS, INC.
  SUBSTANTIALLY EQUIVALENT 1
ZHENGZHOU BESTVIEW ST CO., LTD.
  SUBSTANTIALLY EQUIVALENT 2
ZHUOLU JONTELASER MANUFACTURING TECHNOLOGY CO., LTD
  SUBSTANTIALLY EQUIVALENT 1
ZHUOLU JONTELASER MANUFACTURING TECHNOLOGY CO., LTD.
  SUBSTANTIALLY EQUIVALENT 1
ZIMMER MEDIZINSYSTEME GMBH
  SUBSTANTIALLY EQUIVALENT 1

MDR Year MDR Reports MDR Events
2019 2709 2709
2020 2182 2182
2021 3465 3465
2022 2288 2752
2023 2339 2339
2024 1470 1488

Device Problems MDRs with this Device Problem Events in those MDRs
Break 2999 2999
Adverse Event Without Identified Device or Use Problem 2315 2320
Decrease in Suction 1366 1830
Fracture 899 899
Appropriate Term/Code Not Available 628 628
Defective Device 624 624
Firing Problem 505 505
Detachment of Device or Device Component 457 457
Therapeutic or Diagnostic Output Failure 445 445
Device Displays Incorrect Message 381 381
Failure to Align 380 380
Output Problem 359 359
Overheating of Device 340 340
Device Operational Issue 252 252
Mechanical Problem 240 240
Degraded 231 231
Connection Problem 185 185
Use of Device Problem 180 180
Fire 179 179
Failure to Fire 175 175
Insufficient Information 168 168
Power Problem 156 156
Contamination 139 147
Output below Specifications 136 136
Computer Software Problem 135 135
No Apparent Adverse Event 127 127
Smoking 121 121
Suction Problem 115 115
Failure to Deliver Energy 112 112
Thermal Decomposition of Device 102 102
Misfire 94 94
Loss of or Failure to Bond 91 91
Optical Problem 91 91
Suction Failure 90 90
Electrical /Electronic Property Problem 88 88
Melted 85 85
Incorrect, Inadequate or Imprecise Result or Readings 83 83
Gas Output Problem 81 81
Energy Output Problem 73 73
Material Integrity Problem 69 69
Device Contaminated During Manufacture or Shipping 68 68
Failure to Cut 67 67
Improper or Incorrect Procedure or Method 65 65
Communication or Transmission Problem 59 59
Noise, Audible 55 55
Unexpected/Unintended Radiation Output 54 54
Failure to Power Up 51 51
Material Deformation 50 50
Material Separation 48 48
No Device Output 48 48

Patient Problems MDRs with this Patient Problem Events in those MDRs
No Clinical Signs, Symptoms or Conditions 7132 7439
No Consequences Or Impact To Patient 2119 2119
No Known Impact Or Consequence To Patient 1622 1622
Insufficient Information 678 678
Appropriate Clinical Signs, Symptoms, Conditions Term / Code Not Available 598 765
Burn(s) 445 445
Keratitis 282 283
Visual Impairment 176 176
Blurred Vision 145 145
Pain 127 127
Eye Injury 117 117
Hemorrhage/Bleeding 101 101
No Code Available 93 93
Visual Disturbances 84 87
Scar Tissue 80 80
No Patient Involvement 78 78
Tissue Damage 73 73
Foreign Body In Patient 67 67
Radiation Exposure, Unintended 62 62
Unspecified Tissue Injury 54 54
Superficial (First Degree) Burn 53 53
Blister 52 52
Hematuria 49 49
Urinary Retention 46 46
Swelling/ Edema 45 45
Urinary Tract Infection 41 41
Muscle Weakness 41 41
Inflammation 41 41
Partial thickness (Second Degree) Burn 38 38
Device Embedded In Tissue or Plaque 38 38
Skin Discoloration 37 37
Stenosis 37 37
Patient Problem/Medical Problem 36 36
Eye Pain 36 36
Corneal Abrasion 35 35
Erythema 34 34
Fever 34 34
Dysuria 33 33
Urinary Incontinence 31 31
Headache 30 30
Intracranial Hemorrhage 29 29
Unspecified Kidney or Urinary Problem 29 29
Perforation 28 28
Unspecified Infection 28 28
Foreign Body Sensation in Eye 28 28
Urethral Stenosis/Stricture 27 27
Full thickness (Third Degree) Burn 26 26
Dry Eye(s) 25 25
Hematoma 25 25
Discomfort 25 25

Recalls
Manufacturer Recall Class Date Posted
1 Accure Acne, Inc II Jan-20-2024
2 Advance-Esthetic LLC II Oct-13-2023
3 Aerolase Corporation II Jan-03-2020
4 Angiodynamics, Inc. II Sep-27-2022
5 Angiodynamics, Inc. II Aug-30-2019
6 Boston Scientific Corporation II Jul-21-2023
7 Boston Scientific Corporation III Jul-15-2022
8 Boston Scientific Corporation II Apr-24-2020
9 Boston Scientific Corporation II May-22-2019
10 CLINICAL LASERTHERMIA SYSTEMS AB II Jun-04-2021
11 Candela Corporation II Oct-24-2019
12 Clarus Medical, Llc II Sep-03-2021
13 Dornier Medtech America, Inc. II May-21-2019
14 Inova Lasers LLC II Nov-17-2020
15 Karl Storz Endoscopy II May-13-2024
16 Medtronic Navigation, Inc. II May-06-2020
17 Medtronic Sofamor Danek USA Inc II Jul-23-2020
18 Olympus Corporation of the Americas II Aug-05-2024
19 Olympus Corporation of the Americas II Mar-27-2024
20 Olympus Corporation of the Americas II Jan-18-2024
21 Olympus Corporation of the Americas II Jan-12-2024
22 Olympus Corporation of the Americas II Jan-12-2024
23 Olympus Corporation of the Americas II Jun-28-2022
24 Olympus Corporation of the Americas II Aug-15-2021
25 Quanta System, S.p.A. II Jun-10-2021
26 Ra Medical Systems, Inc. II Apr-01-2020
27 Xintec Corp III Oct-18-2019
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