Pt was received injections into her knees for bilateral osteoarthritis.In the right knee pt received 5 doses of hyalgan injection without a problem.In the left knee, pt received synvisc.After the third injection of synvisc, the pt developed severe pain, a tense effusion and decrease range of motion of the left knee.An aspirate of the knee revealed joint fluid 15,000 rbc, 7,000 wbc and no crystals.The pt was admitted to the hospital for vest, pain control and physical therapy.She improved over a 10 day hospitalization.She was diagnosed with toxic "synouhs" secondary to synvisc injection.
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