The initial reporter stated they received discrepant results for six patient samples tested with elecsys tacrolimus on a cobas e 411 immunoassay analyzer.The initial values were reported outside of the laboratory to the doctor.The doctor questioned the results as they did not correspond to the clinical history of the patients, so the samples were repeated on a second analyzer.The first sample initially resulted in a tacrolimus value of 25.2 ng/ml, which repeated as 11.8 ng/ml.The second sample initially resulted in a tacrolimus value of 9.1 ng/ml, which repeated as 2.7 ng/ml.The third sample initially resulted in a tacrolimus value of 8.5 ng/ml, which repeated as 3.2 ng/ml.The fourth sample initially resulted in a tacrolimus value of 29.5 ng/ml, which repeated as 10 ng/ml.The fifth sample initially resulted in a tacrolimus value of 20.3 ng/ml, which repeated as 13.7 ng/ml.The sixth sample initially resulted in a tacrolimus value of 20.5 ng/ml, which repeated as 11.7 ng/ml.The lot number and expiration date of the tacrolimus reagent were requested, but not provided.
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