Novocure received a report that the patient had been hospitalized on (b)(6) 2022, due to a seizure.Optune therapy was temporarily discontinued.The patient experienced an acute onset of seizure like activity with right sided weakness.The patient's family called emergency medical services and upon arrival, the patient experienced another 30 second episode of flaccidity on the right side with incoherent speech and postictal phase.The patient did not have a history of seizures and was admitted for observation.The patient's neuro-oncologist recommended initiation of anti-seizure medication (levetiracetam 500 mg bid).The patient had no further seizure like activity while hospitalized.On (b)(6) 2022, the patient was discharged home.Per the prescribing physician, the cause of the event was most likely due to radiation effect versus tumor progression.He additionally stated, he could not entirely exclude a contribution of optune to the event.
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