Olympus reviewed the following literature titled "endoscopic submucosal dissection for large duodenal laterally spreading lesions is feasible: a multi-center retrospective study".This multicentric retrospective study sought to assess the effect and safety of esd for large laterally spreading lesions located in the descending duodenum based on multi-center experiences.A total of 51 patients were included.The average procedure time for en bloc resection ranging from 20 to 117 min (median: 45.5 min).Two patients experienced delayed bleeding 3 days after esd and 2 other patients were diagnosed with delayed perforation.All the patients were closely followed up for a median period of 16 months (range 7 to 29 months), and there were no deaths.No residual tumor and local recurrence occurred during follow-up.Esd for laterally spreading lesions of the descending duodenum is a feasible therapeutic procedure and can achieve a favorable en bloc resection rate.Type of adverse events/number of patients: delayed bleeding: case 1, delayed bleeding: case 2, delayed perforation (postoperative fever, mild abdominal pain): case 3, delayed perforation (fever, severe abdominal pain, diffuse peritonitis): case 4, this literature article requires 28 reports.The related patient identifiers are as follows: (b)(6)/case1(female, 64)/kd-620lr; (b)(6)/case1(female, 64)/kd-611l; (b)(6)/case1(female, 64)/fg-8u-1; (b)(6)/case1(female, 64)/nm-4l-1; (b)(6)/case1(female, 64)/fd-410lr; (b)(6)/case1(female, 64)/gif-h260; (b)(6)/case1(female, 64)/maj-339; (b)(6)/case2(male, 63)/kd-620lr; (b)(6)/case2(male, 63)/kd-611l; (b)(6)/case2(male, 63)/fg-8u-1; (b)(6)/case2(male, 63)/nm-4l-1; (b)(6)/case2(male, 63)/fd-410lr; (b)(6)/case2(male, 63)/gif-h260; (b)(6)/case2(male, 63)/maj-339; (b)(6)/case3(male, 57)/kd-620lr; (b)(6)/case3(male, 57)/kd-611l; (b)(6)/case3(male, 57)/fg-8u-1; (b)(6)/case3(male, 57)/nm-4l-1; (b)(6)/case3(male, 57)/fd-410lr; (b)(6)/case3(male, 57)/gif-h260; (b)(6)/case3(male, 57)/maj-339; (b)(6)/case4(female, 61)/kd-620lr; (b)(6)/case4(female, 61)/kd-611l; (b)(6)/case4(female, 61)/fg-8u-1; (b)(6)/case4(female, 61)/nm-4l-1; (b)(6)/case4(female, 61)/fd-410lr; (b)(6)/case4(female, 61)/gif-h260; (b)(6)/case4(female, 61)/maj-339.This medwatch report is for patient identifier (b)(6).There is no report of any olympus device malfunction in any procedure described in this study.
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