The female patient with primary disease of myasthenia gravis experienced following adverse event during immunoadsorption plasmapheresis treatment.The patient received the first immunoadsorption plasmapheresis therapy on (b)(6) 2018 and the second therapy on (b)(6) 2018 with no issue.On (b)(6) 2018, the third therapy was given to the patient.The patient blood pressure was between 110 and 120 mmhg and heart rate was 60 bpm before the therapy.34 minutes after the therapy was started, her blood pressure was decreased to 100 mmhg.41 minutes after the therapy was started, she complained of epigastric pain.Since the blood pressure was decreased to 58 mmhg and heart rate was also decreased to between 30 to 40 bpm, 300 ml of normal saline was administered.After the administration of normal saline, the patient blood pressure was increased to 100 mmhg temporarily, but it was decreased again to 70 mmhg and consciousness level was dropped.To treat the symptoms, oxygen therapy was administered at 1l/min.49 minutes after the treatment was started, the blood pressure was increased to 126 mmhg and level of consciousness was recovered.The blood was returned to the patient.
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