Jiang, b., bender, m.T., westbroek, e.M., campos, j.K., lin, l.-m., xu, r., tamargo, r.J., huang, j., colby, g.P., & coon, a.L.(2018).Procedural complexity independent of p2y12 reaction unit (pru) values is associated with acute in situ thrombosis in pipeline flow diversion of cerebral aneurysms. stroke and vascular neurology, 3(3), 169¿175.Https://doi.Org/10.1136/svn-2018-000150 medtronic received a literature article pertaining to a cohort of 37 ped cases with acute in situ thrombosis (mean age 53.8 years, mean aneurysm size 8.4 mm) that was matched with a cohort of 705 ped cases without intraprocedural thromboembolic events (mean age 56.4 years, mean aneurysm size 6.9 mm).The two groups were evenly matched in patient demographics, previous treatment/subarachnoid hemorrhage (sah), and aneurysm location.The study took place between april 2011 and august 2017, during which a total of 742 consecutive ped/ped flex cases were performed.Of these 742 cases, 37 were identified to have acute in situ thrombosis intraprocedurally.The remaining 705 cases did not have acute ischaemic intraprocedural complications.Intraprocedural thromboembolic complications occurred in 10.8% of the in situ thrombosis group vs 1.2% of the control group.Of these major stroke (nih stroke scale>4) occurred in 4 patients of the in situ thrombosis group and 10 patients of the control group.Minor stroke (nih stroke scale <(><<)>4) occurred in 1 patient of the in situ thrombosis group and 6 patients of the control group.Dependent intracerebral hemorrhage occurred in 1 patient of the in situ thrombosis group and 7 patients of the control group.Remote in tracerebral hemorrhage occurred in 1 patient of the in situ thrombosis group and 1 patient of the control group.Cranial nerve palsy occurred in 9 patients of the control group.Iatrogenic dissection occurred in 1 patient of the in situ thrombosis group and 3 patients of the control group.
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