During attempted intravitreal injection of avastin ((b)(6) pharmacy; lot: 190319ap; ubd: 07/02/2019) the plunger would not advance and the medication was not able to be administered.A second syringe was then used and injection of the avastin was successful.Because the pt required 2 needle sticks, his eye became quite inflamed the next day which required topical durezol and ilevro.Fda safety report id# (b)(4).