FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

Current/Resolved Shortages
Discontinuations
Therapeutic Categories
New and Updated

A drug receives Resolved status when the Drug Shortages Staff (DSS) determines that the market is covered, based on information from all manufacturers. The market is considered covered when supply is available from at least one manufacturer to cover total market demand. However, some manufacturers may not have all presentations available. DSS monitors the supply of products with Resolved status. For the most current supply information, contact the manufacturers.

Generic Name or Active Ingredient	Status
Acetazolamide Injection	Resolved
Albuterol Sulfate Inhalational Solution	Currently in Shortage
Alprostadil (Muse) Suppository	Currently in Shortage
Amifostine Injection	Currently in Shortage
Amino Acids	Currently in Shortage
Amoxapine Tablets	Currently in Shortage
Amoxicillin Oral Powder for Suspension	Currently in Shortage
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate TabletS	Currently in Shortage
Amphetamine Oral Suspension, Extended Release	Resolved
Anagrelide Hydrochloride Capsules	Resolved
Atropine Sulfate Injection	Currently in Shortage
Azacitidine for Injection	Currently in Shortage
Azithromycin (Azasite) Ophthalmic Solution 1%	Currently in Shortage
Bacteriostatic 0.9% Sodium Chloride Injection	Currently in Shortage
Bacteriostatic Water for Injection	Currently in Shortage
Belatacept (Nulojix) Lyophilized Powder for Injection	Currently in Shortage
Belladonna and Opium Suppositories	Currently in Shortage
Bumetanide Injection	Currently in Shortage
Bupivacaine Hydrochloride and Epinephrine Injection	Currently in Shortage
Bupivacaine Hydrochloride Injection	Currently in Shortage
Calcium Gluconate Injection	Currently in Shortage
Cefazolin Injection	Currently in Shortage
Cefixime Oral Capsules	Currently in Shortage
Cefotaxime Sodium Injection	Currently in Shortage
Cefotetan Disodium Injection	Currently in Shortage
Cefoxitin for Injection	Resolved
Ceftazidime and Avibactam (AVYCAZ®) for Injection, 2 grams/0.5 grams	Resolved
Ceftolozane and Tazobactam (Zerbaxa) Injection	Resolved
Chlordiazepoxide Hydrochloride Capsules	Resolved
Chloroprocaine Hydrochloride Injection	Currently in Shortage
Cisatracurium Besylate Injection	Resolved
Collagenase Ointment	Currently in Shortage
Conivaptan Hydrochloride (Vaprisol) in 5% Dextrose Plastic Container	Currently in Shortage
Conjugated Estrogens/Bazedoxifene (DUAVEE) Tablet, Film Coated	Currently in Shortage
Continuous Renal Replacement Therapy (CRRT) Solutions	Resolved
Cyclopentolate Ophthalmic Solution	Currently in Shortage
Cysteamine Hydrochloride Ophthalmic Solution	Resolved
Cysteine Hydrochloride Injection	Resolved
Cytarabine Injection	Currently in Shortage
Dacarbazine Injection	Currently in Shortage
Desmopressin Acetate Nasal Spray	Currently in Shortage
Dexamethasone Sodium Phosphate Injection	Currently in Shortage
Dexmedetomidine Injection	Currently in Shortage
Dextrose 10% Injection	Currently in Shortage
Dextrose 25% Injection	Currently in Shortage
Dextrose 5% Injection	Currently in Shortage
Dextrose 50% Injection	Currently in Shortage
Diazepam Rectal Gel	Currently in Shortage
Diflunisal Tablets	Currently in Shortage
Difluprednate (Durezol) Ophthalmic Emulsion	Resolved
Digoxin Injection	Currently in Shortage
Diltiazem Hydrochloride Injection	Currently in Shortage
Dimercaprol (Bal in Oil) Injection	Resolved
Disopyramide Phosphate (Norpace) Capsules	Currently in Shortage
Dobutamine Hydrochloride Injection	Currently in Shortage
Dopamine Hydrochloride Injection	Currently in Shortage
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution	Resolved
Dorzolamide Hydrochloride Ophthalmic Solution	Resolved
Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution	Currently in Shortage
Edetate Calcium Disodium Injection	Currently in Shortage
Enalaprilat Injection	Currently in Shortage
Epinephrine Injection, 0.1 mg/mL	Currently in Shortage
Epinephrine Injection, Auto-Injector	Currently in Shortage
Erythromycin Ophthalmic Ointment	Currently in Shortage
Etomidate Injection	Currently in Shortage
Famotidine Injection	Resolved
Famotidine Tablets	Resolved
Fentanyl Citrate (Sublimaze) Injection	Currently in Shortage
Floxuridine for Injection	Currently in Shortage
Fludarabine Phosphate Injection	Currently in Shortage
Fludrocortisone Acetate Tablets	Resolved
Fluorescein Injection	Currently in Shortage
Fluorescein Strips	Resolved
Flurazepam Hydrochloride Capsules	Currently in Shortage
Fluvoxamine ER Capsules	Currently in Shortage
Furosemide Injection	Currently in Shortage
Gentamicin Sulfate Injection	Currently in Shortage
Guanfacine Hydrochloride Tablets	Currently in Shortage
Haloperidol Tablets	Resolved
Heparin Sodium and Sodium Chloride 0.9% Injection	Currently in Shortage
Hydralazine Hydrochloride Injection	Resolved
Hydrocortisone Tablets	Resolved
Hydromorphone Hydrochloride Injection	Currently in Shortage
Hydroxocobalamin Injection	Resolved
Hydroxyprogesterone Caproate Injection	Resolved
Hydroxypropyl (Lacrisert) Cellulose Ophthalmic Insert	Currently in Shortage
Hydroxyzine Pamoate Oral Capsules	Resolved
Ibutilide Fumarate Injection	Currently in Shortage
Imipenem and Cilastatin for Injection	Resolved
Indigotindisulfonate Sodium Injection	Currently in Shortage
Iodixanol Injection	Resolved
Iohexol Injection	Resolved
Iomeprol injection	Currently in Shortage
Iopromide (Ultravist) Injection	Resolved
Isoniazid Injection	Currently in Shortage
IV Fat Emulsion	Currently in Shortage
Ketamine Injection	Currently in Shortage
Ketoprofen Capsules	Resolved
Ketorolac Tromethamine Injection	Currently in Shortage
Leucovorin Calcium Lyophilized Powder for Injection	Currently in Shortage
Leuprolide Acetate Injection	Resolved
Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags	Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection	Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine	Currently in Shortage
Lithium Oral Solution	Currently in Shortage
Lorazepam Injection	Currently in Shortage
Loxapine Capsules	Resolved
Lutetium Lu 177 Dotatate (LUTATHERA) Injection	Resolved
Mannitol Injection	Currently in Shortage
Mepivacaine Hydrochloride Injection	Currently in Shortage
Methadone Hydrochloride Injection	Resolved
Methohexital Sodium (Brevital) Injection	Resolved
Methyldopa Tablets	Currently in Shortage
Methylprednisolone Acetate Injection	Currently in Shortage
Metronidazole Injection	Currently in Shortage
Midazolam Injection	Currently in Shortage
Misoprostol Tablets	Resolved
Morphine Sulfate Injection	Currently in Shortage
Multi-Vitamin Infusion (Adult and Pediatric)	Currently in Shortage
Nalbuphine Hydrochloride Injection	Resolved
Nefazodone Hydrochloride Tablets	Resolved
Neomycin Sulfate Tablets	Currently in Shortage
Nizatidine Capsules	Currently in Shortage
Ondansetron Hydrochloride Injection	Resolved
Oxytocin Injection	Currently in Shortage
Paclitaxel Injection (protein-bound particles)	Currently in Shortage
Pantoprazole Sodium for Injection	Currently in Shortage
Parathyroid Hormone (Natpara) Injection	Currently in Shortage
Pentamidine Isethionate (Nebupent) For Inhalation Solution	Resolved
Pentostatin Injection	Currently in Shortage
Physostigmine Salicylate Injection	Currently in Shortage
Pindolol Tablets	Resolved
Potassium Acetate Injection	Currently in Shortage
Potassium Chloride Concentrate Injection	Currently in Shortage
Prednisolone Acetate 1% Ophthalmic Suspension	Resolved
Promethazine (Phenergan) Injection	Currently in Shortage
Propofol Injectable Emulsion	Resolved
Protamine Sulfate Injection	Resolved
Remifentanil Injection	Currently in Shortage
Rifampin Capsules	Currently in Shortage
Rifampin Injection	Currently in Shortage
Rifapentine Tablets	Currently in Shortage
Rocuronium Bromide Injection	Resolved
Ropivacaine Hydrochloride Injection	Currently in Shortage
Scopolamine Transdermal System	Resolved
Semaglutide (Ozempic) Injection	Currently in Shortage
Semaglutide (WEGOVY®) Injection	Currently in Shortage
Sertraline Hydrochloride Oral Solution, USP	Resolved
Sertraline Hydrochloride Tablets	Resolved
Sildenafil Citrate (REVATIO)	Resolved
Sincalide (Kinevac) Lyophilized Powder for Injection	Currently in Shortage
Sodium Acetate Injection	Currently in Shortage
Sodium Bicarbonate Injection	Currently in Shortage
Sodium Chloride 0.9% Injection Bags	Currently in Shortage
Sodium Chloride 14.6% Injection	Currently in Shortage
Sodium Chloride 23.4% Injection	Currently in Shortage
Sodium Chloride Injection, 0.9% Vials and Syringes	Currently in Shortage
Sodium Phosphates Injection	Currently in Shortage
Sterile Water for Injection	Currently in Shortage
Streptozocin (Zanosar) Sterile Powder	Currently in Shortage
Succimer (Chemet) Capsules	Resolved
Sufentanil Citrate Injection	Currently in Shortage
Sulfasalazine Tablets	Currently in Shortage
Tacrolimus Capsules	Resolved
Technetium Tc 99m Sulfur Colloid Injection	Resolved
Technetium TC-99M Mebrofenin Injection	Currently in Shortage
Technetium TC-99m Sodium Pertechnetate Generator	Currently in Shortage
Technetium Tc99m Succimer Injection (DMSA)	Currently in Shortage
Teprotumumab-trbw	Currently in Shortage
TEST ADD REASON SHORTAGE
Thiothixene Capsules	Resolved
Timolol Maleate Ophthalmic Solution	Resolved
Tobramycin Lyophilized Powder for Injection	Resolved
Tocilizumab Injection	Resolved
Triamcinolone Acetonide Injectable Suspension	Currently in Shortage
Triamcinolone Hexacetonide Injectable suspension	Currently in Shortage
Trimethobenzamide Hydrochloride Capsules	Currently in Shortage
Valproate Sodium Injection	Currently in Shortage
Vandetanib Tablets	Resolved
Varenicline Tartrate (Chantix) Tablets	Resolved
Vecuronium Bromide for Injection	Currently in Shortage
Verteporfin (Visudyne) Injection	Currently in Shortage
Vitamin A Palmitate (Aquasol A) Injection	Resolved
Zinc Acetate Capsules	Resolved
Zolpidem Tartrate (Edluar) Sublingual Tablets	Resolved

Discontinuations Listed by Generic Name or Active Ingredient

Companies are required under Section 506C of the Federal Food, Drug, and Cosmetic Act (FD&C Act) (as amended by the Food and Drug Administration Safety and Innovation Act) to notify FDA of a permanent discontinuance of certain drug products, six months in advance, or if that is not possible, as soon as practicable. These drugs include those that are life-supporting, life-sustaining or for use in the prevention or treatment of a debilitating disease or condition, including any such drug used in emergency medical care or during surgery. The discontinuations listed on the site reflect information received from manufacturers and are for informational purposes only.

Withdrawal notifications can be found here: https://www.federalregister.gov

Generic Name or Active Ingredient
Abiraterone Acetate Tablets
Acetaminophen (Ofirmev) Injection
Acetic Acid Otic Solution
Acrivastine and Pseudoephedrine Hydrochloride Capsules
Adalimumab (Humira) Pre-filled Syringe
Adefovir Dipivoxil Tablets
Adenosine Injection
Albuterol Sulfate Aerosol, Metered
Aliskiren and Hydrochlorothiazide Tablets
Alprostadil Injection
Alprostadil Suppository
Aluminum Hydroxide and Magnesium Carbonate (Gaviscon Regular Strength)
Amantadine Hydrochloride Capsules
Ambrisentan Tablets
Amikacin Sulfate Injection
Amiodarone Tablets
Amitriptyline Hydrochloride Tablets
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets
Ampicillin for Injection
Argatroban Injection
Aspirin/Dipyridamole (Aggrenox) Extended Release Capsules
Bacitracin Ophthalmic Ointment
Benzonatate Capsules
Betamethasone Valerate Topical Foam
Bivalirudin in 0.9% Sodium Chloride Injection
Bleomycin Injection
Bosentan Tablets
Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide Oral Syrup
Budesonide Capsules
Bumetanide Injection
Busulfan Injection
Butenafine Hydrochloride Cream
Calcitonin Salmon Nasal Spray
Capreomycin Injection
Captopril Tablets
Captopril/Hydrochlorothiazide Tablets
Carbamazepine Oral Suspension
Cardene IV (nicardipine hydrochloride) 0.2 mg/mL in 5% Dextrose
Caspofungin Acetate Injection
Cefdinir Capsules
Cefdinir Powder for Suspension
Cefotetan Disodium Injection
Ceftazidime (Fortaz) Injection
Cefuroxime Sodium (Zinacef) Injection
Cetirizine Hydrochloride Solution
Chlordiazepoxide Hydrochloride USP, Capsules
Cladribine Injection
Clindamycin and Benzoyl Peroxide Gel, 1%/5%
Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2%/5%
Clindamycin Phosphate Topical Solution 1%
Clobetasol Propionate Ointment
Clobetasol Propionate Ointment 0.05%
Clobetasol Propionate Topical Foam
Clobetasol Propionate Topical Solution 0.05%
Clobetasol Propionate Topical Solution, 0.05%
Clonazepam Tablets
Clonidine Hydrochloride Extended Release Tablets
Clozapine (FazaClo® ) Orally Disintegrating Tablets
Codeine Polistirex and Chlorpheniramine Polistirex Extended-Release Oral Suspension
Cortisone Acetate Tablets
Cytotec (Misoprostol) Tablets
Dacarbazine Injection
Daptomycin Injection
Darifenacin Hydrobromide Tablets
Dasabuvir Sodium; Ombitasvir; Paritaprevir; Ritonavir (Viekira XR) Tablets
Daunorubicin Hydrochloride Injection
Daunorubicin Hydrochloride Injection (Novaplus®* Label)
Deferasirox Tablets
Desmopressin Acetate Injection
Desogestrel and Ethinyl Estradiol Tablets (ORTHO-CEPT)
Dextroamphetamine Sulfate Extended-Release Capsules
Diazepam Oral Solution (Concentrate)
Diclofenac Sodium Extended Release Tablets
Didanosine Delayed-Release Capsules USP
Diflorasone Diacetate Ointment, 0.05%
Diltiazem Hydrochloride Injection
Disulfiram Tablets
Dofetilide Capsules
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution
Dorzolamide Hydrochloride Ophthalmic Solution
Doxepin Hydrochloride Oral Solution
Doxercalciferol Injection
Doxycycline Capsules
Doxycycline Hyclate Powder for Suspension
Doxycycline Hyclate Tablets
Efavirenz Capsules
Efavirenz Tablets
Epoprostenol Sodium for Injection and Sterile Diluent for Epoprostenol Sodium for Injection
Eptifibatide Injection
Ergotamine Tartrate and Caffeine (Cafergot) Tablets
Ertapenem Injection
Esomeprazole Sodium for Injection
Ethambutol Hydrochloride Tablets
Etoposide (Toposar) Injection
Exenatide (BYDUREON) Extended Release for Injectable Suspension
Febuxostat Tablets
Fenoldopam Mesylate (Corlopam) Injection
Finasteride Tablets
Fluconazole (Diflucan) Tablets
Flumazenil Injection
Fluocinonide Gel 0.05%
Fluocinonide Ointment 0.05%
Fluocinonide Topical Solution
Fluorometholone Ophthalmic Ointment
Fluoxetine Capsules
Fosphenytoin Sodium Injection
Furosemide Injection
Furosemide Oral Solution
Furosemide Oral Solution, 10 mg/mL
Gallium Citrate GA- 67 Injection
Gemifloxacin Mesylate (Factive) Tablets
Gentamicin and Prednisolone Acetate Ophthalmic Suspension
Gentamicin Sulfate and Prednisolone Acetate Ophthalmic Ointment
Gentamicin Sulfate Solution
Glipizide Tablets
Glipizide XL Tablets
Glucagon Injection
Glyburide and Metformin Hydrochloride Tablets
Granisetron Hydrochloride Injection
Haloperidol Decanoate Injection
Histrelin Acetate Implant
Hydrochlorothiazide and Lisinopril Tablets
Hydrochlorothiazide and Spironolactone (Aldactazide) Tablets
Hydrocodone Bitartrate and Homatropine Methylbromide Oral Solution
Hydrocortisone Acetate Suppository
Hyoscyamine Sulfate Injection
Idarubicin Hydrochloride Injection
Ifosfamide Injection
Imipramine Tablets
Indomethacin Capsules
Indomethacin Injection
Insulin Lispro (Humalog Mix50/50)
Interferon alfa-2b, Recombinant for Injection
Iohexol Injection
Iopamidol (Isovue) Injection
Lactulose Solution
Lamivudine and Tenofovir Disoproxil Fumarate Tablets
Lamivudine and Zidovudine Tablets
Lamivudine Oral Solution
Lamivudine Tablets
Lanoxin (digoxin) Tablets
Leucovorin Calcium for Injection
Levoleucovorin Calcium Pentahydrate Injection
Levoleucovorin Injection
Lidocaine HCl Topical Jelly
Lindane Shampoo 1%
Linezolid Injection
Liothyronine Sodium Tablets
Lisinopril Tablets
Loxapine Capsules
Meclizine Hydrochloride Tablets
Medroxyprogesterone Acetate Injectable Suspension
Megestrol Acetate Oral Suspension
Megestrol Acetate Suspension
Meloxicam Tablets
Memantine Hydrochloride Extended-Release Capsules
Mepivacaine Hydrochloride Injection
Mesalamine (CANASA®) Suppositories
Metaxalone Tablets
Metformin Hydrochloride Extended Release Tablets
Methimazole Tablets
Methocarbamol Injection
Methyldopa Tablets
Methylprednisolone Acetate Injectable Suspension
Methylprednisolone Tablets
Metoclopramide Tablets
Metoprolol Tartrate Tablets
Metronidazole (Flagyl) Tablets
Metronidazole Injection
Metronidazole Vaginal Gel
Mirtazapine Orally Disintegrating Tablets
Mitoxantrone Injection
Mometasone Furoate Monohydrate Nasal Spray
Montelukast Sodium Chewable Tablet
Montelukast Sodium Tablets
Morphine Sulfate Extended-Release Tablets
Moxifloxacin (Moxeza) Ophthalmic Solution
Nafcillin Injection
Nafcillin Sodium Injection
Naratriptan Hydrochloride Tablets
Nateglinide Tablets
Nebivolol Hydrochloride Tablets
Nedocromil Sodium Ophthalmic Solution
Nesiritide Powder (NATRECOR) for Injection
Nevirapine (Viramune) Tablets
Nevirapine Oral Suspension
Norepinephrine Bitartrate Injection
Norethindrone (NOR QD) Tablets
Nystatin and Triamcinolone Acetonide Cream
Nystatin and Triamcinolone Acetonide Ointment
Nystatin Ointment
Octreotide Acetate Injection
Olanzapine and Fluoxetine (Symbyax) Capsules
Olopatadine Hydrochloride Nasal Spray
Ombitasvir; Paritaprevir; Ritonavir (Technivie) Tablets
Omeprazole and Sodium Bicarbonate Powder for Suspension
Ondansetron Hydrochloride Injection
Oxaliplatin Injection
Oxcarbazepine Oral Suspension
Oxybutynin Chloride Syrup
Paclitaxel Injection, USP
Paliperidone Extended Release Tablets
Peginterferon alfa-2b (Sylatron)
Pentoxifylline Extended-Release Tablets
Phenobarbital Oral Solution
Pioglitazone Hydrochloride Tablets
Pioglitazone/Metformin HCl (ACTOPLUS MET®) Tablets
Piroxicam Capsules
Polymyxin B Sulfate and Trimethoprim Sulfate Ophthalmic Solution
Pramipexole Dihydrochloride Extended Release Tablets
Prednisolone Sodium Phosphate Oral Solution
Pregabalin Capsules
Procainamide Hydrochloride Injection
Procardia Capsules
ProHance® (Gadoteridol) Injection
Promethazine Hydrochloride Injection, Solution
Propafenone Hydrochloride Tablets
Propofol Injectable Emulsion
Ranolazine Extended Release Tablets
Repaglinide Tablets
Rifampin (Rifadin) Capsules
Rifampin Capsules
Rifampin/Isoniazid (Rifamate) Capsules
Rifampin/Isoniazid/Pyrazinamide (Rifater) Tablets
Risankizumab-rzaa Injection
Risedronate Sodium Tablets
Risedronate Tablets
Risperidone Tablets
Ropivacaine Hydrochloride Injection
Rosuvastatin Calcium Tablets
Samarium SM 153 Lexidronam (Quadramet) Injection
Saquinavir Mesylate (Invirase) 200mg Capsules
Sclerosol Intrapleural Aerosol
Selenium Sulfide Lotion, 2.5%
Simeprevir Capsules
Simvastatin (Zocor) Tablets
Simvastatin Tablets
Somatropin Recombinant (Humatrope) Injection
Spironolactone Tablets
Stavudine Capsules
Streptozocin (Zanosar) Sterile Powder
Sulfacetamide Sodium and Prednisolone Acetate Ophthalmic Ointment
Sulfacetamide Sodium Solution
Sumatriptan (Sumavel DosePro) Injection
Sumatriptan Succinate Injection
Synercid Injection
Talwin (Pentazocine Lactate Injection, USP, CIV)
Telmisartan and Amlodipine (Twynsta) Tablets
Temozolomide Capsules
Testosterone Transdermal Gel
Thallous Chloride TL 201 Injection
Tipranavir Oral Solution
Tizanidine Hydrochloride Capsules
Tizanidine Hydrochloride Tablets
Topotecan Injection
Trandolapril Tablets
Tranexamic Acid Tablets
Triamcinolone Acetonide Cream
Triamterene and Hydrochlorothiazide Tablets
Trimethobenzamide Hydrochloride Capsules
Umbrasilib Tosylate Tablets
Valproic Acid Oral Solution
Vancomycin Hydrochloride for Injection
Vecuronium Bromide for Injection
Vecuronium Bromide Injection
Verapamil Hydrochloride Tablets
Vibramycin Hyclate (Doxycycline Hyclate) for Suspension
Vincristine Sulfate (Vincasar PFS) Injection
Vinorelbine Tartrate Injection
Voriconazole Tablets
Zafirlukast Oral Tablets
Zolpidem Tartrate Oral Spray