FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

Current/Resolved Shortages
Discontinuations
Therapeutic Categories
New and Updated

A drug receives Resolved status when the Drug Shortages Staff (DSS) determines that the market is covered, based on information from all manufacturers. The market is considered covered when supply is available from at least one manufacturer to cover total market demand. However, some manufacturers may not have all presentations available. DSS monitors the supply of products with Resolved status. For the most current supply information, contact the manufacturers.

Generic Name or Active Ingredient	Status
Acetazolamide Injection	Currently in Shortage
Amifostine Injection	Currently in Shortage
Amino Acids	Currently in Shortage
Amoxapine Tablets	Currently in Shortage
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets	Currently in Shortage
Amphetamine Oral Suspension, Extended Release	Currently in Shortage
Anagrelide Hydrochloride Capsules	Resolved
Atropine Sulfate Injection	Currently in Shortage
Azacitidine for Injection	Currently in Shortage
Azithromycin (Azasite) Ophthalmic Solution 1%	Currently in Shortage
Bacteriostatic 0.9% Sodium Chloride Injection	Currently in Shortage
Bacteriostatic Water for Injection	Currently in Shortage
Belatacept (Nulojix) Lyophilized Powder for Injection	Currently in Shortage
Bumetanide Injection	Currently in Shortage
Bupivacaine Hydrochloride and Epinephrine Injection	Currently in Shortage
Bupivacaine Hydrochloride Injection	Currently in Shortage
Calcium Disodium Versenate Injection	Currently in Shortage
Calcium Gluconate Injection	Currently in Shortage
Cefazolin Injection	Currently in Shortage
Cefixime Oral Capsules	Currently in Shortage
Cefotaxime Sodium Injection	Currently in Shortage
Cefotetan Disodium Injection	Currently in Shortage
Cefoxitin for Injection	Resolved
Ceftazidime and Avibactam (AVYCAZ®) for Injection, 2 grams/0.5 grams	Resolved
Ceftolozane and Tazobactam (Zerbaxa) Injection	Resolved
Chlordiazepoxide Hydrochloride Capsules	Currently in Shortage
Chloroprocaine Hydrochloride Injection	Currently in Shortage
Cisatracurium Besylate Injection	Resolved
Conivaptan Hydrochloride (Vaprisol) in 5% Dextrose Plastic Container	Currently in Shortage
Continuous Renal Replacement Therapy (CRRT) Solutions	Currently in Shortage
Cortisone Acetate Tablets	Currently in Shortage
Cyclopentolate Ophthalmic Solution	Currently in Shortage
Cysteamine Hydrochloride Ophthalmic Solution	Currently in Shortage
Cysteine Hydrochloride Injection	Resolved
Cytarabine Injection	Currently in Shortage
Dacarbazine Injection	Currently in Shortage
Deferoxamine Mesylate for Injection, USP	Resolved
Desmopressin Acetate Nasal Spray	Currently in Shortage
Dexamethasone Sodium Phosphate Injection	Currently in Shortage
Dexmedetomidine Injection	Currently in Shortage
Dextrose 10% Injection	Currently in Shortage
Dextrose 25% Injection	Currently in Shortage
Dextrose 5% Injection	Currently in Shortage
Dextrose 50% Injection	Currently in Shortage
Diflunisal Tablets	Currently in Shortage
Difluprednate (Durezol) Ophthalmic Emulsion	Resolved
Digoxin Injection	Currently in Shortage
Diltiazem Hydrochloride Injection	Currently in Shortage
Dimercaprol (Bal in Oil) Injection	Resolved
Disopyramide Phosphate (Norpace) Capsules	Currently in Shortage
Dobutamine Hydrochloride Injection	Currently in Shortage
Dopamine Hydrochloride Injection	Currently in Shortage
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution	Resolved
Dorzolamide Hydrochloride Ophthalmic Solution	Resolved
Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution	Currently in Shortage
Enalaprilat Injection	Currently in Shortage
Epinephrine Injection, 0.1 mg/mL	Currently in Shortage
Epinephrine Injection, Auto-Injector	Currently in Shortage
Erythromycin Ophthalmic Ointment	Resolved
Etomidate Injection	Resolved
Famotidine Injection	Resolved
Famotidine Tablets	Resolved
Fentanyl Citrate (Sublimaze) Injection	Currently in Shortage
Floxuridine for Injection	Currently in Shortage
Fludarabine Phosphate Injection	Currently in Shortage
Fludrocortisone Acetate Tablets	Resolved
Fluorescein Injection	Currently in Shortage
Fluorescein Strips	Resolved
Fluvoxamine ER Capsules	Currently in Shortage
Furosemide Injection	Currently in Shortage
Gemifloxacin Mesylate (Factive) Tablets	Currently in Shortage
Gentamicin Sulfate Injection	Currently in Shortage
Guanfacine Hydrochloride Tablets	Currently in Shortage
Haloperidol Tablets	Resolved
Heparin Sodium and Sodium Chloride 0.9% Injection	Currently in Shortage
Hydralazine Hydrochloride Injection	Resolved
Hydrocortisone Tablets	Currently in Shortage
Hydromorphone Hydrochloride Injection	Currently in Shortage
Hydroxocobalamin Injection	Resolved
Hydroxyprogesterone Caproate Injection	Resolved
Hydroxypropyl (Lacrisert) Cellulose Ophthalmic Insert	Currently in Shortage
Hydroxyzine Pamoate Oral Capsules	Resolved
Ibutilide Fumarate Injection	Currently in Shortage
Imipenem and Cilastatin for Injection	Currently in Shortage
Iodixanol (Visipaque) Injection	Currently in Shortage
Iohexol (Omnipaque) Injection	Currently in Shortage
Isoniazid Injection	Currently in Shortage
Ketamine Injection	Currently in Shortage
Ketoprofen Capsules	Currently in Shortage
Ketorolac Tromethamine Injection	Currently in Shortage
Leucovorin Calcium Lyophilized Powder for Injection	Currently in Shortage
Leuprolide Acetate Injection	Currently in Shortage
Levetiracetam Extended-Release Oral Tablets, USP	Resolved
Levetiracetam Immediate-Release Oral Tablets, USP	Resolved
Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags	Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection	Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine	Currently in Shortage
Lipid Injection	Currently in Shortage
Lithium Oral Solution	Currently in Shortage
Lorazepam Injection	Currently in Shortage
Loxapine Capsules	Currently in Shortage
Lutetium Lu 177 Dotatate (LUTATHERA) Injection	Currently in Shortage
Mannitol Injection	Currently in Shortage
Mepivacaine Hydrochloride Injection	Currently in Shortage
Methadone Hydrochloride Injection	Resolved
Methohexital Sodium (Brevital) Injection	Resolved
Methyldopa Tablets	Currently in Shortage
Methylprednisolone Acetate Injection	Currently in Shortage
Metoclopramide Injection, USP	Resolved
Metronidazole Injection	Currently in Shortage
Midazolam Injection	Currently in Shortage
Misoprostol Tablets	Resolved
Morphine Sulfate Injection	Currently in Shortage
Multi-Vitamin Infusion (Adult and Pediatric)	Currently in Shortage
Nalbuphine Hydrochloride Injection	Resolved
Nefazodone Hydrochloride Tablets	Currently in Shortage
Nizatidine Capsules	Currently in Shortage
Ondansetron Hydrochloride Injection	Resolved
Oxytocin Injection (Synthetic)	Resolved
Paclitaxel Injection (protein-bound particles)	Currently in Shortage
Pantoprazole Sodium for Injection	Currently in Shortage
Parathyroid Hormone (Natpara) Injection	Currently in Shortage
Pentamidine Isethionate (Nebupent) For Inhalation Solution	Resolved
Pentostatin Injection	Currently in Shortage
Phenytoin Sodium Injection, USP	Resolved
Physostigmine Salicylate Injection	Currently in Shortage
Pindolol Tablets	Resolved
Potassium Acetate Injection	Currently in Shortage
Potassium Chloride Concentrate Injection	Currently in Shortage
Prednisolone Acetate 1% Ophthalmic Suspension	Resolved
Progesterone Injection, USP	Resolved
Promethazine (Phenergan) Injection	Currently in Shortage
Propofol Injectable Emulsion	Currently in Shortage
Protamine Sulfate Injection	Currently in Shortage
Rifampin Capsules	Currently in Shortage
Rifampin Injection	Currently in Shortage
Rifapentine Tablets	Currently in Shortage
Rocuronium Bromide Injection	Resolved
Ropivacaine Hydrochloride Injection	Currently in Shortage
Sclerosol Intrapleural Aerosol	Currently in Shortage
Scopolamine Transdermal System	Resolved
Semaglutide (WEGOVY®) Injection	Currently in Shortage
Sertraline Hydrochloride Oral Solution, USP	Resolved
Sertraline Hydrochloride Tablets	Resolved
Sildenafil Citrate (REVATIO)	Resolved
Sincalide (Kinevac) Lyophilized Powder for Injection	Currently in Shortage
Sodium Acetate Injection	Currently in Shortage
Sodium Bicarbonate Injection	Currently in Shortage
Sodium Chloride 0.9% Injection Bags	Currently in Shortage
Sodium Chloride 14.6% Injection	Currently in Shortage
Sodium Chloride 23.4% Injection	Currently in Shortage
Sodium Chloride Injection USP, 0.9% Vials and Syringes	Currently in Shortage
Sodium Phosphates Injection	Currently in Shortage
Sterile Water for Injection	Currently in Shortage
Streptozocin Powder for Injection	Currently in Shortage
Succimer (Chemet) Capsules	Resolved
Sufentanil Citrate Injection	Currently in Shortage
Sulfasalazine Tablets	Currently in Shortage
Tacrolimus Capsules	Resolved
Technetium Tc 99m Sulfur Colloid Injection	Resolved
Technetium TC-99M Mebrofenin Injection	Currently in Shortage
Technetium Tc99m Succimer Injection (DMSA)	Currently in Shortage
Teprotumumab-trbw	Currently in Shortage
Thiothixene Capsules	Currently in Shortage
Timolol Maleate Ophthalmic Solution	Resolved
Tobramycin Lyophilized Powder for Injection	Resolved
Tocilizumab Injection	Resolved
Triamcinolone Acetonide Injectable Suspension	Currently in Shortage
Triamcinolone Hexacetonide Injectable suspension	Currently in Shortage
Trimethobenzamide Hydrochloride Capsules	Currently in Shortage
Valproate Sodium Injection	Currently in Shortage
Varenicline Tartrate (Chantix) Tablets	Currently in Shortage
Vecuronium Bromide for Injection	Currently in Shortage
Vitamin A Palmitate (Aquasol A) Injection	Resolved
Zinc Acetate Capsules	Resolved
Zolpidem Tartrate (Edluar) Sublingual Tablets	Resolved

Discontinuations Listed by Generic Name or Active Ingredient

Companies are required under Section 506C of the Federal Food, Drug, and Cosmetic Act (FD&C Act) (as amended by the Food and Drug Administration Safety and Innovation Act) to notify FDA of a permanent discontinuance of certain drug products, six months in advance, or if that is not possible, as soon as practicable. These drugs include those that are life-supporting, life-sustaining or for use in the prevention or treatment of a debilitating disease or condition, including any such drug used in emergency medical care or during surgery. The discontinuations listed on the site reflect information received from manufacturers and are for informational purposes only.

Withdrawal notifications can be found here: https://www.federalregister.gov

Generic Name or Active Ingredient
Abiraterone Acetate Tablets
Acrivastine and Pseudoephedrine Hydrochloride Capsules
Adalimumab (Humira) Pre-filled Syringe
Albuterol Sulfate Aerosol, Metered
Aliskiren and Hydrochlorothiazide Tablets
Alprostadil Suppository
Aluminum Hydroxide and Magnesium Carbonate (Gaviscon Regular Strength)
Amantadine Hydrochloride Capsules
Ambrisentan Tablets
Amiodarone Tablets
Amitriptyline Hydrochloride Tablets
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets
Ampicillin for Injection
Aspirin/Dipyridamole (Aggrenox) Extended Release Capsules
Bacitracin Ophthalmic Ointment
Benzonatate Capsules
Betamethasone Valerate Topical Foam
Budesonide Capsules
Busulfan Injection
Capreomycin Injection
Captopril Tablets
Captopril/Hydrochlorothiazide Tablets
Cardene IV (nicardipine hydrochloride) 0.2 mg/mL in 5% Dextrose
Caspofungin Acetate Injection
Cefdinir Capsules
Cefdinir Powder for Suspension
Ceftazidime (Fortaz) Injection
Cefuroxime Sodium (Zinacef) Injection
Chlordiazepoxide Hydrochloride USP, Capsules
Clindamycin and Benzoyl Peroxide Gel, 1%/5%
Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2%/5%
Clindamycin Phosphate Topical Solution 1%
Clobetasol Propionate Ointment 0.05%
Clobetasol Propionate Topical Foam
Clobetasol Propionate Topical Solution, 0.05%
Clonazepam Tablets
Clonidine Hydrochloride Extended Release Tablets
Clozapine (FazaClo® ) Orally Disintegrating Tablets
Cytotec (Misoprostol) Tablets
Daptomycin Injection
Darifenacin Hydrobromide Tablets
Dasabuvir Sodium; Ombitasvir; Paritaprevir; Ritonavir (Viekira XR) Tablets
Deferasirox Tablets
Desogestrel and Ethinyl Estradiol Tablets (ORTHO-CEPT)
Dextroamphetamine Sulfate Extended-Release Capsules
Diazepam Oral Solution (Concentrate)
Diclofenac Sodium Extended Release Tablets
Didanosine Delayed-Release Capsules USP
Diflorasone Diacetate Ointment, 0.05%
Diltiazem Hydrochloride Injection
Disulfiram Tablets
Dofetilide Capsules
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution
Dorzolamide Hydrochloride Ophthalmic Solution
Doxycycline Capsules
Doxycycline Hyclate Powder for Suspension
Efavirenz Tablets
Ergotamine Tartrate and Caffeine (Cafergot) Tablets
Esomeprazole Sodium for Injection
Ethambutol Hydrochloride Tablets
Exenatide (BYDUREON) Extended Release for Injectable Suspension
Febuxostat Tablets
Finasteride Tablets
Flumazenil Injection
Fluocinonide Gel 0.05%
Fluocinonide Ointment 0.05%
Fluocinonide Topical Solution
Fluorometholone Ophthalmic Ointment
Fluoxetine Capsules
Fosphenytoin Sodium Injection
Furosemide Oral Solution
Furosemide Oral Solution, 10 mg/mL
Gemcitabine Hydrochloride Injection
Gentamicin Sulfate and Prednisolone Acetate Ophthalmic Ointment
Glipizide Tablets
Histrelin Acetate Implant
Hydrochlorothiazide and Lisinopril Tablets
Hydrocodone Bitartrate and Homatropine Methylbromide Oral Solution
Hydrocortisone Acetate Suppository
Imipramine Tablets
Indomethacin Capsules
Iopamidol (Isovue) Injection
Ketoprofen Capsules
Lamivudine and Tenofovir Disoproxil Fumarate Tablets
Lamivudine and Zidovudine Tablets
Lamivudine Tablets
Lanoxin (digoxin) Tablets
Levoleucovorin Calcium Pentahydrate Injection
Levoleucovorin Injection
Lidocaine HCl Topical Jelly
Liothyronine Sodium Tablets
Lisinopril Tablets
Loxapine Capsules
Meclizine Hydrochloride Tablets
Megestrol Acetate Suspension
Meloxicam Tablets
Memantine Hydrochloride Extended-Release Capsules
Mesalamine (CANASA®) Suppositories
Metaxalone Tablets
Metformin Hydrochloride Extended Release Tablets
Methimazole Tablets
Methocarbamol Injection
Methyldopa Tablets
Methylprednisolone Tablets
Metoclopramide Tablets
Metoprolol Tartrate Tablets
Metronidazole (Flagyl) Tablets
Mirtazapine Orally Disintegrating Tablets
Mometasone Furoate Monohydrate Nasal Spray
Montelukast Sodium Chewable Tablet
Montelukast Sodium Tablets
Morphine Sulfate Extended-Release Tablets
Moxifloxacin (Moxeza) Ophthalmic Solution
Nafcillin Injection
Nafcillin Sodium Injection
Naratriptan Hydrochloride Tablets
Nedocromil Sodium Ophthalmic Solution
Nesiritide Powder (NATRECOR) for Injection
Nevirapine (Viramune) Tablets
Nevirapine Oral Suspension
Norethindrone (NOR QD) Tablets
Nystatin and Triamcinolone Acetonide Cream
Nystatin and Triamcinolone Acetonide Ointment
Olanzapine and Fluoxetine (Symbyax) Capsules
Ombitasvir; Paritaprevir; Ritonavir (Technivie) Tablets
Omeprazole and Sodium Bicarbonate Powder for Suspension
Ondansetron Hydrochloride Injection
Oxybutynin Chloride Syrup
Paclitaxel Injection, USP
Peginterferon alfa-2b (Sylatron)
Pentoxifylline Extended-Release Tablets
Phenobarbital Oral Solution
Pioglitazone Hydrochloride Tablets
Pioglitazone/Metformin HCl (ACTOPLUS MET®) Tablets
Piroxicam Capsules
Pramipexole Dihydrochloride Extended Release Tablets
Procardia Capsules
ProHance® (Gadoteridol) Injection
Promethazine Hydrochloride Injection, Solution
Propafenone Hydrochloride Tablets
Propofol Injectable Emulsion
Ranolazine Extended Release Tablets
Repaglinide Tablets
Rifampin (Rifadin) Capsules
Rifampin/Isoniazid (Rifamate) Capsules
Rifampin/Isoniazid/Pyrazinamide (Rifater) Tablets
Risedronate Sodium Tablets
Risedronate Tablets
Risperidone Tablets
Samarium SM 153 Lexidronam (Quadramet) Injection
Saquinavir Mesylate (Invirase) 200mg Capsules
Simeprevir Capsules
Simvastatin (Zocor) Tablets
Simvastatin Tablets
Somatropin Recombinant (Humatrope) Injection
Spironolactone Tablets
Stavudine Capsules
Sulfacetamide Sodium and Prednisolone Acetate Ophthalmic Ointment
Sumatriptan (Sumavel DosePro) Injection
Sumatriptan Succinate Injection
Talwin (Pentazocine Lactate Injection, USP, CIV)
Telmisartan and Amlodipine (Twynsta) Tablets
Temozolomide Capsules
Tipranavir Oral Solution
Tizanidine Hydrochloride Capsules
Tizanidine Hydrochloride Tablets
Trandolapril Tablets
Tranexamic Acid Tablets
Triamcinolone Acetonide Cream
Triamterene and Hydrochlorothiazide Tablets
Trimethobenzamide Hydrochloride Capsules
Umbrasilib Tosylate Tablets
Valproic Acid Oral Solution
Vancomycin Hydrochloride for Injection
Vibramycin Hyclate (Doxycycline Hyclate) for Suspension
Vinorelbine Tartrate Injection
Zafirlukast Oral Tablets